Pipoxolan suppresses the inflammatory factors of NF‐κB, AP‐1, and STATs, but activates the antioxidative factor Nrf2 in LPS‐stimulated RAW 264.7 murine macrophage cells

Although pipoxolan (PIPO) is a smooth muscle relaxant, its anti‐inflammatory capability has not been studied. Therefore, we investigated the anti‐inflammatory molecular mechanisms of PIPO in lipopolysaccharide (LPS)‐induced RAW 264.7 macrophages. In this study, we used the MTT assay to evaluate the...

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Detalles Bibliográficos
Autores principales: Lin, Yu‐Hsien, Lin, Yu‐Jung, Chang, Ting‐Hsuan, Chang, Yun‐Hsuan, Lim, Yun‐Ping, Chung, Jing‐Gung, Hsieh, Wen‐Tsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689704/
https://www.ncbi.nlm.nih.gov/pubmed/32677756
http://dx.doi.org/10.1002/tox.23000

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