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Transmission of viral pathogens in a social network of university students: the eX-FLU study
Previous research on respiratory infection transmission among university students has primarily focused on influenza. In this study, we explore potential transmission events for multiple respiratory pathogens in a social contact network of university students. University students residing in on-camp...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689784/ https://www.ncbi.nlm.nih.gov/pubmed/32792023 http://dx.doi.org/10.1017/S0950268820001806 |
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author | Zivich, P.N. Eisenberg, M.C. Monto, A.S. Uzicanin, A. Baric, R. S. Sheahan, T. P. Rainey, J. J. Gao, H. Aiello, A. E. |
author_facet | Zivich, P.N. Eisenberg, M.C. Monto, A.S. Uzicanin, A. Baric, R. S. Sheahan, T. P. Rainey, J. J. Gao, H. Aiello, A. E. |
author_sort | Zivich, P.N. |
collection | PubMed |
description | Previous research on respiratory infection transmission among university students has primarily focused on influenza. In this study, we explore potential transmission events for multiple respiratory pathogens in a social contact network of university students. University students residing in on-campus housing (n = 590) were followed for the development of influenza-like illness for 10-weeks during the 2012–13 influenza season. A contact network was built using weekly self-reported contacts, class schedules, and housing information. We considered a transmission event to have occurred if students were positive for the same pathogen and had a network connection within a 14-day period. Transmitters were individuals who had onset date prior to their infected social contact. Throat and nasal samples were analysed for multiple viruses by RT-PCR. Five viruses were involved in 18 transmission events (influenza A, parainfluenza virus 3, rhinovirus, coronavirus NL63, respiratory syncytial virus). Transmitters had higher numbers of co-infections (67%). Identified transmission events had contacts reported in small classes (33%), dormitory common areas (22%) and dormitory rooms (17%). These results suggest that targeting person-to-person interactions, through measures such as isolation and quarantine, could reduce transmission of respiratory infections on campus. |
format | Online Article Text |
id | pubmed-7689784 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-76897842020-12-04 Transmission of viral pathogens in a social network of university students: the eX-FLU study Zivich, P.N. Eisenberg, M.C. Monto, A.S. Uzicanin, A. Baric, R. S. Sheahan, T. P. Rainey, J. J. Gao, H. Aiello, A. E. Epidemiol Infect Original Paper Previous research on respiratory infection transmission among university students has primarily focused on influenza. In this study, we explore potential transmission events for multiple respiratory pathogens in a social contact network of university students. University students residing in on-campus housing (n = 590) were followed for the development of influenza-like illness for 10-weeks during the 2012–13 influenza season. A contact network was built using weekly self-reported contacts, class schedules, and housing information. We considered a transmission event to have occurred if students were positive for the same pathogen and had a network connection within a 14-day period. Transmitters were individuals who had onset date prior to their infected social contact. Throat and nasal samples were analysed for multiple viruses by RT-PCR. Five viruses were involved in 18 transmission events (influenza A, parainfluenza virus 3, rhinovirus, coronavirus NL63, respiratory syncytial virus). Transmitters had higher numbers of co-infections (67%). Identified transmission events had contacts reported in small classes (33%), dormitory common areas (22%) and dormitory rooms (17%). These results suggest that targeting person-to-person interactions, through measures such as isolation and quarantine, could reduce transmission of respiratory infections on campus. Cambridge University Press 2020-08-14 /pmc/articles/PMC7689784/ /pubmed/32792023 http://dx.doi.org/10.1017/S0950268820001806 Text en © The Author(s) 2020 http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Paper Zivich, P.N. Eisenberg, M.C. Monto, A.S. Uzicanin, A. Baric, R. S. Sheahan, T. P. Rainey, J. J. Gao, H. Aiello, A. E. Transmission of viral pathogens in a social network of university students: the eX-FLU study |
title | Transmission of viral pathogens in a social network of university students: the eX-FLU study |
title_full | Transmission of viral pathogens in a social network of university students: the eX-FLU study |
title_fullStr | Transmission of viral pathogens in a social network of university students: the eX-FLU study |
title_full_unstemmed | Transmission of viral pathogens in a social network of university students: the eX-FLU study |
title_short | Transmission of viral pathogens in a social network of university students: the eX-FLU study |
title_sort | transmission of viral pathogens in a social network of university students: the ex-flu study |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689784/ https://www.ncbi.nlm.nih.gov/pubmed/32792023 http://dx.doi.org/10.1017/S0950268820001806 |
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