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Epidemiological situation of leprosy in a province in China: a long time to diagnosis and a high rate of deformity

BACKGROUND: This epidemiological study aimed to analyse both the distribution and characteristics of leprosy in an endemic province in Northwest China. METHODS: The medical records of leprosy patients in the province of Shaanxi, China, from 1998 to 2018 were collected from the Chinese Leprosy Manage...

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Autores principales: Zhang, Qing-Ping, Li, Ge, Li, Chao, Lin, Zhao-Xing, Chen, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690005/
https://www.ncbi.nlm.nih.gov/pubmed/33238966
http://dx.doi.org/10.1186/s12889-020-09933-6
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author Zhang, Qing-Ping
Li, Ge
Li, Chao
Lin, Zhao-Xing
Chen, Ping
author_facet Zhang, Qing-Ping
Li, Ge
Li, Chao
Lin, Zhao-Xing
Chen, Ping
author_sort Zhang, Qing-Ping
collection PubMed
description BACKGROUND: This epidemiological study aimed to analyse both the distribution and characteristics of leprosy in an endemic province in Northwest China. METHODS: The medical records of leprosy patients in the province of Shaanxi, China, from 1998 to 2018 were collected from the Chinese Leprosy Management Information System (LEPMIS). Epidemiological variables were analysed in this study. RESULTS: A total of 477 new cases were diagnosed between 1998 and 2018 in this region. The average annual detection rate was 0.070/100,000 population, and the average annual prevalence was 0.305/100,000 population. The mean age of the newly diagnosed patients was 46.7 years, and the ratio of males to females was 2.5:1. There were 399 cases (83.6%) of multibacillary (MB) leprosy. One hundred forty-eight patients (31.0%) had grade 2 disability. The mean diagnosis time for new cases was 62.0 months. CONCLUSION: This epidemiological study showed that the characteristics of newly diagnosed leprosy cases in our province were a long time to diagnosis and a high rate of deformity, indicating the need for actions focusing on early diagnosis and treatment and strengthening the detection of leprosy in low-prevalence areas.
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spelling pubmed-76900052020-11-30 Epidemiological situation of leprosy in a province in China: a long time to diagnosis and a high rate of deformity Zhang, Qing-Ping Li, Ge Li, Chao Lin, Zhao-Xing Chen, Ping BMC Public Health Research Article BACKGROUND: This epidemiological study aimed to analyse both the distribution and characteristics of leprosy in an endemic province in Northwest China. METHODS: The medical records of leprosy patients in the province of Shaanxi, China, from 1998 to 2018 were collected from the Chinese Leprosy Management Information System (LEPMIS). Epidemiological variables were analysed in this study. RESULTS: A total of 477 new cases were diagnosed between 1998 and 2018 in this region. The average annual detection rate was 0.070/100,000 population, and the average annual prevalence was 0.305/100,000 population. The mean age of the newly diagnosed patients was 46.7 years, and the ratio of males to females was 2.5:1. There were 399 cases (83.6%) of multibacillary (MB) leprosy. One hundred forty-eight patients (31.0%) had grade 2 disability. The mean diagnosis time for new cases was 62.0 months. CONCLUSION: This epidemiological study showed that the characteristics of newly diagnosed leprosy cases in our province were a long time to diagnosis and a high rate of deformity, indicating the need for actions focusing on early diagnosis and treatment and strengthening the detection of leprosy in low-prevalence areas. BioMed Central 2020-11-25 /pmc/articles/PMC7690005/ /pubmed/33238966 http://dx.doi.org/10.1186/s12889-020-09933-6 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Zhang, Qing-Ping
Li, Ge
Li, Chao
Lin, Zhao-Xing
Chen, Ping
Epidemiological situation of leprosy in a province in China: a long time to diagnosis and a high rate of deformity
title Epidemiological situation of leprosy in a province in China: a long time to diagnosis and a high rate of deformity
title_full Epidemiological situation of leprosy in a province in China: a long time to diagnosis and a high rate of deformity
title_fullStr Epidemiological situation of leprosy in a province in China: a long time to diagnosis and a high rate of deformity
title_full_unstemmed Epidemiological situation of leprosy in a province in China: a long time to diagnosis and a high rate of deformity
title_short Epidemiological situation of leprosy in a province in China: a long time to diagnosis and a high rate of deformity
title_sort epidemiological situation of leprosy in a province in china: a long time to diagnosis and a high rate of deformity
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690005/
https://www.ncbi.nlm.nih.gov/pubmed/33238966
http://dx.doi.org/10.1186/s12889-020-09933-6
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