Cargando…

Real-World Comparison of Human and Software Image Assessment in Acute Ischemic Stroke Patients’ Qualification for Reperfusion Treatment

Our aim was to compare human and computer accuracy in reading medical images of acute stroke patients. We analyzed data of patients who underwent assessment of Alberta Stroke Program Early CT Score (ASPECTS) and CT Perfusion (CTP) via Rapid Processing of Perfusion and Diffusion (RAPID) software RAPI...

Descripción completa

Detalles Bibliográficos
Autores principales: Lasocha, Bartlomiej, Pulyk, Roman, Brzegowy, Pawel, Latacz, Pawel, Slowik, Agnieszka, Popiela, Tadeusz J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690255/
https://www.ncbi.nlm.nih.gov/pubmed/33105544
http://dx.doi.org/10.3390/jcm9113383
_version_ 1783614032365748224
author Lasocha, Bartlomiej
Pulyk, Roman
Brzegowy, Pawel
Latacz, Pawel
Slowik, Agnieszka
Popiela, Tadeusz J.
author_facet Lasocha, Bartlomiej
Pulyk, Roman
Brzegowy, Pawel
Latacz, Pawel
Slowik, Agnieszka
Popiela, Tadeusz J.
author_sort Lasocha, Bartlomiej
collection PubMed
description Our aim was to compare human and computer accuracy in reading medical images of acute stroke patients. We analyzed data of patients who underwent assessment of Alberta Stroke Program Early CT Score (ASPECTS) and CT Perfusion (CTP) via Rapid Processing of Perfusion and Diffusion (RAPID) software RAPID ASPECTS, and RAPID CTP), compared to radiologist reports and manual measurements. We compared volumes calculated by RAPID CTP software with those selected by scanner-equipped software (GE). For reference, follow-up images were manually assessed in accordance with the Alberta Stroke Program Early CT Score (ASPECTS) territories retrospectively. Although exact ASPECTS score agreement between the automatic and manual methods, and between each method and follow-up, was poor, crossing of the threshold for reperfusion therapy was characterized by an 80% match. CT perfusion analyses yielded only slight agreement (kappa = 0.193) in the qualification of patients for therapy. Either automatic or manual scoring methods of non-contrast images imply similar clinical decisions in real-world circumstances. However, volume measurements performed by fully automatic and manually assisted systems are not comparable. Thresholds devised and validated for computer algorithms are not compatible with measurements performed manually using other software and should not be applied to setups other than those with which they were developed.
format Online
Article
Text
id pubmed-7690255
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-76902552020-11-27 Real-World Comparison of Human and Software Image Assessment in Acute Ischemic Stroke Patients’ Qualification for Reperfusion Treatment Lasocha, Bartlomiej Pulyk, Roman Brzegowy, Pawel Latacz, Pawel Slowik, Agnieszka Popiela, Tadeusz J. J Clin Med Article Our aim was to compare human and computer accuracy in reading medical images of acute stroke patients. We analyzed data of patients who underwent assessment of Alberta Stroke Program Early CT Score (ASPECTS) and CT Perfusion (CTP) via Rapid Processing of Perfusion and Diffusion (RAPID) software RAPID ASPECTS, and RAPID CTP), compared to radiologist reports and manual measurements. We compared volumes calculated by RAPID CTP software with those selected by scanner-equipped software (GE). For reference, follow-up images were manually assessed in accordance with the Alberta Stroke Program Early CT Score (ASPECTS) territories retrospectively. Although exact ASPECTS score agreement between the automatic and manual methods, and between each method and follow-up, was poor, crossing of the threshold for reperfusion therapy was characterized by an 80% match. CT perfusion analyses yielded only slight agreement (kappa = 0.193) in the qualification of patients for therapy. Either automatic or manual scoring methods of non-contrast images imply similar clinical decisions in real-world circumstances. However, volume measurements performed by fully automatic and manually assisted systems are not comparable. Thresholds devised and validated for computer algorithms are not compatible with measurements performed manually using other software and should not be applied to setups other than those with which they were developed. MDPI 2020-10-22 /pmc/articles/PMC7690255/ /pubmed/33105544 http://dx.doi.org/10.3390/jcm9113383 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lasocha, Bartlomiej
Pulyk, Roman
Brzegowy, Pawel
Latacz, Pawel
Slowik, Agnieszka
Popiela, Tadeusz J.
Real-World Comparison of Human and Software Image Assessment in Acute Ischemic Stroke Patients’ Qualification for Reperfusion Treatment
title Real-World Comparison of Human and Software Image Assessment in Acute Ischemic Stroke Patients’ Qualification for Reperfusion Treatment
title_full Real-World Comparison of Human and Software Image Assessment in Acute Ischemic Stroke Patients’ Qualification for Reperfusion Treatment
title_fullStr Real-World Comparison of Human and Software Image Assessment in Acute Ischemic Stroke Patients’ Qualification for Reperfusion Treatment
title_full_unstemmed Real-World Comparison of Human and Software Image Assessment in Acute Ischemic Stroke Patients’ Qualification for Reperfusion Treatment
title_short Real-World Comparison of Human and Software Image Assessment in Acute Ischemic Stroke Patients’ Qualification for Reperfusion Treatment
title_sort real-world comparison of human and software image assessment in acute ischemic stroke patients’ qualification for reperfusion treatment
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690255/
https://www.ncbi.nlm.nih.gov/pubmed/33105544
http://dx.doi.org/10.3390/jcm9113383
work_keys_str_mv AT lasochabartlomiej realworldcomparisonofhumanandsoftwareimageassessmentinacuteischemicstrokepatientsqualificationforreperfusiontreatment
AT pulykroman realworldcomparisonofhumanandsoftwareimageassessmentinacuteischemicstrokepatientsqualificationforreperfusiontreatment
AT brzegowypawel realworldcomparisonofhumanandsoftwareimageassessmentinacuteischemicstrokepatientsqualificationforreperfusiontreatment
AT lataczpawel realworldcomparisonofhumanandsoftwareimageassessmentinacuteischemicstrokepatientsqualificationforreperfusiontreatment
AT slowikagnieszka realworldcomparisonofhumanandsoftwareimageassessmentinacuteischemicstrokepatientsqualificationforreperfusiontreatment
AT popielatadeuszj realworldcomparisonofhumanandsoftwareimageassessmentinacuteischemicstrokepatientsqualificationforreperfusiontreatment