Cargando…

Discovery of Targetable Genetic Alterations in NSCLC Patients with Different Metastatic Patterns Using a MassARRAY-Based Circulating Tumor DNA Assay

Circulating tumor DNA (ctDNA) has shown great promise as a minimally invasive liquid biopsy for personalized cancer diagnostics especially among metastatic patients. Here, we used a novel sensitive assay to detect clinically relevant mutations in ctDNA in blood plasma from metastatic non-small cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Belloum, Yassine, Janning, Melanie, Mohme, Malte, Simon, Ronald, Kropidlowski, Jolanthe, Sartori, Alexander, Irwin, Darryl, Westphal, Manfred, Lamszus, Katrin, Loges, Sonja, Riethdorf, Sabine, Pantel, Klaus, Wikman, Harriet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690267/ https://www.ncbi.nlm.nih.gov/pubmed/33105541 http://dx.doi.org/10.3390/cells9112337

Ejemplares similares

Detection and Monitoring of Tumor-Derived Mutations in Circulating Tumor DNA Using the UltraSEEK Lung Panel on the MassARRAY System in Metastatic Non-Small Cell Lung Cancer Patients
por: van der Leest, Paul, et al.
Publicado: (2023)

Circulating tumor cells and extracellular vesicles as liquid biopsy markers in neuro-oncology: prospects and limitations
por: Westphal,, Manfred, et al.
Publicado: (2022)

EGFR and HER3 expression in circulating tumor cells and tumor tissue from non-small cell lung cancer patients
por: Scharpenseel, Heather, et al.
Publicado: (2019)

Clinical Relevance of Loss of 11p15 in Primary and Metastatic Breast Cancer: Association with Loss of PRKCDBP Expression in Brain Metastases
por: Wikman, Harriet, et al.
Publicado: (2012)

Frequency of Circulating Tumor Cells (CTC) in Patients with Brain Metastases: Implications as a Risk Assessment Marker in Oligo-Metastatic Disease
por: Hanssen, Annkathrin, et al.
Publicado: (2018)

Clonality of circulating tumor cells in breast cancer brain metastasis patients
por: Riebensahm, Carlotta, et al.
Publicado: (2019)

Clinical relevance of blood-based ctDNA analysis: mutation detection and beyond
por: Keller, Laura, et al.
Publicado: (2020)

Characterization of RARRES1 Expression on Circulating Tumor Cells as Unfavorable Prognostic Marker in Resected Pancreatic Ductal Adenocarcinoma Patients
por: Nitschke, Christine, et al.
Publicado: (2022)

Circulating Tumour Cell Release after Cement Augmentation of Vertebral Metastases
por: Mohme, Malte, et al.
Publicado: (2017)

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients
por: Wikman, Harriet, et al.
Publicado: (2014)

Clinical determinants impacting overall survival of patients with operable brain metastases from non-small cell lung cancer
por: Piffko, Andras, et al.
Publicado: (2022)

CD74 and CD44 Expression on CTCs in Cancer Patients with Brain Metastasis
por: Loreth, Desiree, et al.
Publicado: (2021)

Molecular profiling of an osseous metastasis in glioblastoma during checkpoint inhibition: potential mechanisms of immune escape
por: Mohme, Malte, et al.
Publicado: (2020)

Comparative evaluation of PD‐L1 expression in cytology imprints, circulating tumour cells and tumour tissue in non‐small cell lung cancer patients
por: Abdo, Mustafa, et al.
Publicado: (2023)

Detection of Circulating Tumor Cells in Non-Small Cell Lung Cancer
por: Hanssen, Annkathrin, et al.
Publicado: (2015)

PATH-05 Challenge and clinical relevance of a non-matching classifier output in genome-wide DNA methylation analysis for CNS neoplasms in pediatric and adolescent patients
por: Drexler, Richard, et al.
Publicado: (2022)

Chimeric Antigen Receptor T Cells in Glioblastoma—Current Concepts and Promising Future
por: Kringel, Rebecca, et al.
Publicado: (2023)

Determination of PD-L1 Expression in Circulating Tumor Cells of NSCLC Patients and Correlation with Response to PD-1/PD-L1 Inhibitors
por: Janning, Melanie, et al.
Publicado: (2019)

Circulating Cancer Associated Macrophage-like Cells as a Potential New Prognostic Marker in Pancreatic Ductal Adenocarcinoma
por: Nitschke, Christine, et al.
Publicado: (2022)

MassArray analysis of genomic susceptibility variants in ovarian cancer
por: Verma, Sonali, et al.
Publicado: (2020)

Combined Liquid Biopsy Methylation Analysis of CADM1 and MAL in Cervical Cancer Patients
por: Leffers, Markus, et al.
Publicado: (2022)

A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells
por: Hvichia, G.E., et al.
Publicado: (2016)

PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression
por: Hohensee, Ina, et al.
Publicado: (2016)

Relevance of PTEN loss in brain metastasis formation in breast cancer patients
por: Wikman, Harriet, et al.
Publicado: (2012)

Analysis of PTEN Methylation Patterns in Soft Tissue Sarcomas by MassARRAY Spectrometry
por: Yin, Liang, et al.
Publicado: (2013)

Genetic and epigenetic profiling identifies two distinct classes of spinal meningiomas
por: Ricklefs, Franz L., et al.
Publicado: (2022)

Characterization of different CTC subpopulations in non-small cell lung cancer
por: Hanssen, Annkathrin, et al.
Publicado: (2016)

EGFR as a Target for Glioblastoma Treatment: An Unfulfilled Promise
por: Westphal, Manfred, et al.
Publicado: (2017)

Pre-Analytical and Analytical Variables of Label-Independent Enrichment and Automated Detection of Circulating Tumor Cells in Cancer Patients
por: Koch, Claudia, et al.
Publicado: (2020)

Determination of somatic oncogenic mutations linked to target-based therapies using MassARRAY technology
por: Ibarrola-Villava, Maider, et al.
Publicado: (2016)

MassARRAY-based single nucleotide polymorphism analysis in breast cancer of north Indian population
por: Bakshi, Divya, et al.
Publicado: (2020)

Targeting the EGF receptor family in non-small cell lung cancer—increased complexity and future perspectives
por: Boch, Tobias, et al.
Publicado: (2022)

Genotyping of Single Nucleotide Polymorphisms in DNA Isolated from Serum Using Sequenom MassARRAY Technology
por: Clendenen, Tess V., et al.
Publicado: (2015)

Performance of MassARRAY system for the detection of SARS-CoV-2 compared to real-time PCR
por: AlMutawa, Fatimah, et al.
Publicado: (2023)

Assessment of common somatic mutations of EGFR, KRAS, BRAF, NRAS in pulmonary non-small cell carcinoma using iPLEX(®) HS, a new highly sensitive assay for the MassARRAY(®) System
por: Sutton, Bobbie C., et al.
Publicado: (2017)

Establishment and application of a multiplex genetic mutation-detection method of lung cancer based on MassARRAY platform
por: Tian, Hong-Xia, et al.
Publicado: (2016)

Screening of genetic alterations related to non-syndromic hearing loss using MassARRAY iPLEX® technology
por: Svidnicki, Maria Carolina CCosta CMelo, et al.
Publicado: (2015)

MassARRAY analysis of twelve cancer related SNPs in esophageal squamous cell carcinoma in J&K, India
por: Shah, Ruchi, et al.
Publicado: (2020)

Genetic evaluation of the variants using MassARRAY in non-small cell lung cancer among North Indians
por: Bhat, Gh. Rasool, et al.
Publicado: (2021)

Evaluation of 41 single nucleotide polymorphisms in canine diffuse large B-cell lymphomas using MassARRAY
por: Sirivisoot, Sirintra, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_a8cmqg21uac67fni5ae095qa14