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The PTEN Conundrum: How to Target PTEN-Deficient Prostate Cancer

Loss of the tumor suppressor phosphatase and tensin homologue deleted on chromosome 10 (PTEN), which negatively regulates the PI3K–AKT–mTOR pathway, is strongly linked to advanced prostate cancer progression and poor clinical outcome. Accordingly, several therapeutic approaches are currently being e...

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Detalles Bibliográficos
Autores principales:	Turnham, Daniel J., Bullock, Nicholas, Dass, Manisha S., Staffurth, John N., Pearson, Helen B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690430/ https://www.ncbi.nlm.nih.gov/pubmed/33105713 http://dx.doi.org/10.3390/cells9112342

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