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Polymerase chain reaction-proven tuberculous anterior segment mass mimicking juvenile xanthogranuloma in a child

Mass lesions arising from the anterior segment in children involving the iris and ciliary body can be of myogenic, neurogenic, or hematogenic/vascular origin. These include nevi, melanomas, adenoma, adenocarcinoma, cysts, metastatic tumours among others. Multiple iris mass lesions due to tuberculosi...

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Detalles Bibliográficos
Autores principales: Mahesh, Meenakshi, Sudharshan, S, Khetan, Vikas, Janani, M K, Krishnakumar, Subramanian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690467/
https://www.ncbi.nlm.nih.gov/pubmed/32823470
http://dx.doi.org/10.4103/ijo.IJO_852_20
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author Mahesh, Meenakshi
Sudharshan, S
Khetan, Vikas
Janani, M K
Krishnakumar, Subramanian
author_facet Mahesh, Meenakshi
Sudharshan, S
Khetan, Vikas
Janani, M K
Krishnakumar, Subramanian
author_sort Mahesh, Meenakshi
collection PubMed
description Mass lesions arising from the anterior segment in children involving the iris and ciliary body can be of myogenic, neurogenic, or hematogenic/vascular origin. These include nevi, melanomas, adenoma, adenocarcinoma, cysts, metastatic tumours among others. Multiple iris mass lesions due to tuberculosis in children are rare. We present an uncommon atypical presentation of multiple anterior segment mass lesions referred to us as neoplasia. Although excision biopsy can be diagnostic, it was deferred and anterior chamber tap was done. Aqueous cytology was suspicious of juvenile xanthogranuloma (JXG) but polymerase chain reaction (PCR) confirmed tuberculous etiology. Treatment with antituberculous therapy (ATT) and steroids lead to complete resolution of the lesions.
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spelling pubmed-76904672020-12-30 Polymerase chain reaction-proven tuberculous anterior segment mass mimicking juvenile xanthogranuloma in a child Mahesh, Meenakshi Sudharshan, S Khetan, Vikas Janani, M K Krishnakumar, Subramanian Indian J Ophthalmol Case Reports Mass lesions arising from the anterior segment in children involving the iris and ciliary body can be of myogenic, neurogenic, or hematogenic/vascular origin. These include nevi, melanomas, adenoma, adenocarcinoma, cysts, metastatic tumours among others. Multiple iris mass lesions due to tuberculosis in children are rare. We present an uncommon atypical presentation of multiple anterior segment mass lesions referred to us as neoplasia. Although excision biopsy can be diagnostic, it was deferred and anterior chamber tap was done. Aqueous cytology was suspicious of juvenile xanthogranuloma (JXG) but polymerase chain reaction (PCR) confirmed tuberculous etiology. Treatment with antituberculous therapy (ATT) and steroids lead to complete resolution of the lesions. Wolters Kluwer - Medknow 2020-09 2020-08-20 /pmc/articles/PMC7690467/ /pubmed/32823470 http://dx.doi.org/10.4103/ijo.IJO_852_20 Text en Copyright: © 2020 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Reports
Mahesh, Meenakshi
Sudharshan, S
Khetan, Vikas
Janani, M K
Krishnakumar, Subramanian
Polymerase chain reaction-proven tuberculous anterior segment mass mimicking juvenile xanthogranuloma in a child
title Polymerase chain reaction-proven tuberculous anterior segment mass mimicking juvenile xanthogranuloma in a child
title_full Polymerase chain reaction-proven tuberculous anterior segment mass mimicking juvenile xanthogranuloma in a child
title_fullStr Polymerase chain reaction-proven tuberculous anterior segment mass mimicking juvenile xanthogranuloma in a child
title_full_unstemmed Polymerase chain reaction-proven tuberculous anterior segment mass mimicking juvenile xanthogranuloma in a child
title_short Polymerase chain reaction-proven tuberculous anterior segment mass mimicking juvenile xanthogranuloma in a child
title_sort polymerase chain reaction-proven tuberculous anterior segment mass mimicking juvenile xanthogranuloma in a child
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690467/
https://www.ncbi.nlm.nih.gov/pubmed/32823470
http://dx.doi.org/10.4103/ijo.IJO_852_20
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