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Isolated intraocular histiocytosis—A rarely reported entity masquerading clinically as uveitis
An immunocompetent, 25-year-old gentleman with bilateral chronic uveitis presented to various uveitis clinics at different points of time with documented typical clinical features of Toxoplasma Chorioretinitis (Headlight in fog appearance), Behcet's Disease (Hypopyon with peripheral retinal vas...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690470/ https://www.ncbi.nlm.nih.gov/pubmed/32823479 http://dx.doi.org/10.4103/ijo.IJO_565_20 |
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author | Moreker, Mayur R Dudani, Ajay I Sharma, Tanuj R Patel, Keyuri Smruti, B K |
author_facet | Moreker, Mayur R Dudani, Ajay I Sharma, Tanuj R Patel, Keyuri Smruti, B K |
author_sort | Moreker, Mayur R |
collection | PubMed |
description | An immunocompetent, 25-year-old gentleman with bilateral chronic uveitis presented to various uveitis clinics at different points of time with documented typical clinical features of Toxoplasma Chorioretinitis (Headlight in fog appearance), Behcet's Disease (Hypopyon with peripheral retinal vasculitis), and Presumed Ocular Tuberculosis (Granulomatous Intermediate Uveitis with positive Interferon-gamma release assay) and had been treated with anti-toxoplasma drugs, oral prednisolone, and immunomodulation with oral Mycophenolate/oral Azathioprine to no avail. After cytological examination of vitreous aspirate, he was found to have non-Langerhans cell Histiocytosis which responded to chemotherapy with Vinblastine and Cyclophosphamide. |
format | Online Article Text |
id | pubmed-7690470 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-76904702020-12-30 Isolated intraocular histiocytosis—A rarely reported entity masquerading clinically as uveitis Moreker, Mayur R Dudani, Ajay I Sharma, Tanuj R Patel, Keyuri Smruti, B K Indian J Ophthalmol Case Reports An immunocompetent, 25-year-old gentleman with bilateral chronic uveitis presented to various uveitis clinics at different points of time with documented typical clinical features of Toxoplasma Chorioretinitis (Headlight in fog appearance), Behcet's Disease (Hypopyon with peripheral retinal vasculitis), and Presumed Ocular Tuberculosis (Granulomatous Intermediate Uveitis with positive Interferon-gamma release assay) and had been treated with anti-toxoplasma drugs, oral prednisolone, and immunomodulation with oral Mycophenolate/oral Azathioprine to no avail. After cytological examination of vitreous aspirate, he was found to have non-Langerhans cell Histiocytosis which responded to chemotherapy with Vinblastine and Cyclophosphamide. Wolters Kluwer - Medknow 2020-09 2020-08-20 /pmc/articles/PMC7690470/ /pubmed/32823479 http://dx.doi.org/10.4103/ijo.IJO_565_20 Text en Copyright: © 2020 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Reports Moreker, Mayur R Dudani, Ajay I Sharma, Tanuj R Patel, Keyuri Smruti, B K Isolated intraocular histiocytosis—A rarely reported entity masquerading clinically as uveitis |
title | Isolated intraocular histiocytosis—A rarely reported entity masquerading clinically as uveitis |
title_full | Isolated intraocular histiocytosis—A rarely reported entity masquerading clinically as uveitis |
title_fullStr | Isolated intraocular histiocytosis—A rarely reported entity masquerading clinically as uveitis |
title_full_unstemmed | Isolated intraocular histiocytosis—A rarely reported entity masquerading clinically as uveitis |
title_short | Isolated intraocular histiocytosis—A rarely reported entity masquerading clinically as uveitis |
title_sort | isolated intraocular histiocytosis—a rarely reported entity masquerading clinically as uveitis |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690470/ https://www.ncbi.nlm.nih.gov/pubmed/32823479 http://dx.doi.org/10.4103/ijo.IJO_565_20 |
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