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Involvement of the Peripheral Nervous System in Episodic Ataxias

Episodic ataxias comprise a group of inherited disorders, which have a common hallmark—transient attacks of ataxia. The genetic background is heterogeneous and the causative genes are not always identified. Furthermore, the clinical presentation, including intraictal and interictal symptoms, as well...

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Autores principales: Koźmiński, Wojciech, Pera, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690566/
https://www.ncbi.nlm.nih.gov/pubmed/33105744
http://dx.doi.org/10.3390/biomedicines8110448
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author Koźmiński, Wojciech
Pera, Joanna
author_facet Koźmiński, Wojciech
Pera, Joanna
author_sort Koźmiński, Wojciech
collection PubMed
description Episodic ataxias comprise a group of inherited disorders, which have a common hallmark—transient attacks of ataxia. The genetic background is heterogeneous and the causative genes are not always identified. Furthermore, the clinical presentation, including intraictal and interictal symptoms, as well as the retention and progression of neurological deficits, is heterogeneous. Spells of ataxia can be accompanied by other symptoms—mostly from the central nervous system. However, in some of episodic ataxias involvement of peripheral nervous system is a part of typical clinical picture. This review intends to provide an insight into involvement of peripheral nervous system in episodic ataxias.
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spelling pubmed-76905662020-11-27 Involvement of the Peripheral Nervous System in Episodic Ataxias Koźmiński, Wojciech Pera, Joanna Biomedicines Review Episodic ataxias comprise a group of inherited disorders, which have a common hallmark—transient attacks of ataxia. The genetic background is heterogeneous and the causative genes are not always identified. Furthermore, the clinical presentation, including intraictal and interictal symptoms, as well as the retention and progression of neurological deficits, is heterogeneous. Spells of ataxia can be accompanied by other symptoms—mostly from the central nervous system. However, in some of episodic ataxias involvement of peripheral nervous system is a part of typical clinical picture. This review intends to provide an insight into involvement of peripheral nervous system in episodic ataxias. MDPI 2020-10-22 /pmc/articles/PMC7690566/ /pubmed/33105744 http://dx.doi.org/10.3390/biomedicines8110448 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Koźmiński, Wojciech
Pera, Joanna
Involvement of the Peripheral Nervous System in Episodic Ataxias
title Involvement of the Peripheral Nervous System in Episodic Ataxias
title_full Involvement of the Peripheral Nervous System in Episodic Ataxias
title_fullStr Involvement of the Peripheral Nervous System in Episodic Ataxias
title_full_unstemmed Involvement of the Peripheral Nervous System in Episodic Ataxias
title_short Involvement of the Peripheral Nervous System in Episodic Ataxias
title_sort involvement of the peripheral nervous system in episodic ataxias
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690566/
https://www.ncbi.nlm.nih.gov/pubmed/33105744
http://dx.doi.org/10.3390/biomedicines8110448
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