Cargando…
Involvement of the Peripheral Nervous System in Episodic Ataxias
Episodic ataxias comprise a group of inherited disorders, which have a common hallmark—transient attacks of ataxia. The genetic background is heterogeneous and the causative genes are not always identified. Furthermore, the clinical presentation, including intraictal and interictal symptoms, as well...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690566/ https://www.ncbi.nlm.nih.gov/pubmed/33105744 http://dx.doi.org/10.3390/biomedicines8110448 |
_version_ | 1783614096941252608 |
---|---|
author | Koźmiński, Wojciech Pera, Joanna |
author_facet | Koźmiński, Wojciech Pera, Joanna |
author_sort | Koźmiński, Wojciech |
collection | PubMed |
description | Episodic ataxias comprise a group of inherited disorders, which have a common hallmark—transient attacks of ataxia. The genetic background is heterogeneous and the causative genes are not always identified. Furthermore, the clinical presentation, including intraictal and interictal symptoms, as well as the retention and progression of neurological deficits, is heterogeneous. Spells of ataxia can be accompanied by other symptoms—mostly from the central nervous system. However, in some of episodic ataxias involvement of peripheral nervous system is a part of typical clinical picture. This review intends to provide an insight into involvement of peripheral nervous system in episodic ataxias. |
format | Online Article Text |
id | pubmed-7690566 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-76905662020-11-27 Involvement of the Peripheral Nervous System in Episodic Ataxias Koźmiński, Wojciech Pera, Joanna Biomedicines Review Episodic ataxias comprise a group of inherited disorders, which have a common hallmark—transient attacks of ataxia. The genetic background is heterogeneous and the causative genes are not always identified. Furthermore, the clinical presentation, including intraictal and interictal symptoms, as well as the retention and progression of neurological deficits, is heterogeneous. Spells of ataxia can be accompanied by other symptoms—mostly from the central nervous system. However, in some of episodic ataxias involvement of peripheral nervous system is a part of typical clinical picture. This review intends to provide an insight into involvement of peripheral nervous system in episodic ataxias. MDPI 2020-10-22 /pmc/articles/PMC7690566/ /pubmed/33105744 http://dx.doi.org/10.3390/biomedicines8110448 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Koźmiński, Wojciech Pera, Joanna Involvement of the Peripheral Nervous System in Episodic Ataxias |
title | Involvement of the Peripheral Nervous System in Episodic Ataxias |
title_full | Involvement of the Peripheral Nervous System in Episodic Ataxias |
title_fullStr | Involvement of the Peripheral Nervous System in Episodic Ataxias |
title_full_unstemmed | Involvement of the Peripheral Nervous System in Episodic Ataxias |
title_short | Involvement of the Peripheral Nervous System in Episodic Ataxias |
title_sort | involvement of the peripheral nervous system in episodic ataxias |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690566/ https://www.ncbi.nlm.nih.gov/pubmed/33105744 http://dx.doi.org/10.3390/biomedicines8110448 |
work_keys_str_mv | AT kozminskiwojciech involvementoftheperipheralnervoussysteminepisodicataxias AT perajoanna involvementoftheperipheralnervoussysteminepisodicataxias |