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Combination Therapy of High-Dose Rabeprazole Plus Metronomic Capecitabine in Advanced Gastro-Intestinal Cancer: A Randomized Phase II Trial
SIMPLE SUMMARY: This is the first phase II study of high dose rabeprazole repurposing (1.5 mg/kg bid, three days a week) combined with metronomic capecitabine (mCAP), 1500 mg/daily, in gastrointestinal cancer, aimed at evaluating the activity and safety of high-dose proton pump inhibitor in combinat...
Autores principales: | Roberto, Michela, Romiti, Adriana, Mazzuca, Federica, Milano, Annalisa, D’Antonio, Chiara, Lionetto, Luana, Falcone, Rosa, Strigari, Lidia, Simmaco, Maurizio, Fais, Stefano, Marchetti, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690608/ https://www.ncbi.nlm.nih.gov/pubmed/33105819 http://dx.doi.org/10.3390/cancers12113084 |
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