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Incidence of Melanoma in Catalonia, Spain, Is Rapidly Increasing in the Elderly Population. A Multicentric Cohort Study

The incidence of melanoma has been increasing worldwide during recent decades. The objective of the study was to analyse the trends in incidence for in situ and invasive melanoma in the Spanish region of Catalonia during the period of 2008–2017. We designed a cross-sectional study with an age-period...

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Autores principales: Podlipnik, Sebastian, Carrera, Cristina, Boada, Aram, Richarz, Nina, Marcoval, Joaquim, Ferreres, Josep Ramón, Bodet, Domingo, Martí, Rosa María, Segura, Sonia, Sabat, Mireia, Dalmau, Joan, Quintana, Mònica, Azon, Antoni, Curcó, Neus, Formigon, Manel, Olivella-Garcés, María Rosa, Zaballos, Pedro, Sola, Joaquim, Galvany, Loida, Baliu-Piqué, Carola, Alegre, Marta, Pasquali, Paola, Malvehy, Josep, Puig, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690683/
https://www.ncbi.nlm.nih.gov/pubmed/33113930
http://dx.doi.org/10.3390/jcm9113396
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author Podlipnik, Sebastian
Carrera, Cristina
Boada, Aram
Richarz, Nina
Marcoval, Joaquim
Ferreres, Josep Ramón
Bodet, Domingo
Martí, Rosa María
Segura, Sonia
Sabat, Mireia
Dalmau, Joan
Quintana, Mònica
Azon, Antoni
Curcó, Neus
Formigon, Manel
Olivella-Garcés, María Rosa
Zaballos, Pedro
Sola, Joaquim
Galvany, Loida
Baliu-Piqué, Carola
Alegre, Marta
Pasquali, Paola
Malvehy, Josep
Puig, Susana
author_facet Podlipnik, Sebastian
Carrera, Cristina
Boada, Aram
Richarz, Nina
Marcoval, Joaquim
Ferreres, Josep Ramón
Bodet, Domingo
Martí, Rosa María
Segura, Sonia
Sabat, Mireia
Dalmau, Joan
Quintana, Mònica
Azon, Antoni
Curcó, Neus
Formigon, Manel
Olivella-Garcés, María Rosa
Zaballos, Pedro
Sola, Joaquim
Galvany, Loida
Baliu-Piqué, Carola
Alegre, Marta
Pasquali, Paola
Malvehy, Josep
Puig, Susana
author_sort Podlipnik, Sebastian
collection PubMed
description The incidence of melanoma has been increasing worldwide during recent decades. The objective of the study was to analyse the trends in incidence for in situ and invasive melanoma in the Spanish region of Catalonia during the period of 2008–2017. We designed a cross-sectional study with an age-period-cohort analysis of melanoma patient data from the Network of Melanoma Centres in Catalonia. Our database covered a population of over seven million and included a total of 8626 patients with incident melanoma. The main outcome measures were crude and age-standardised incidence rates to the European 2013 standard population. Joinpoint regression models were used to evaluate the population trends. We observed an increase in the age-standardised incidence rate (per 100,000 population) of all melanoma subtypes from 11.56 in 2008 to 13.78 in 2017 with an average annual percent change (AAPC) of 3.5%. This incidence increase was seen exclusively in the older population. Moreover, the stratified analysis showed a statistically significant increase in the age-standardised incidence rate for invasive (AAPC 2.1%) and in situ melanoma (AAPC 6.5%). In conclusion, the incidence of melanoma has continued to increase in the elderly population over recent decades, with a rapidly increasing trend of in situ melanomas and the lentigo maligna subtype.
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spelling pubmed-76906832020-11-27 Incidence of Melanoma in Catalonia, Spain, Is Rapidly Increasing in the Elderly Population. A Multicentric Cohort Study Podlipnik, Sebastian Carrera, Cristina Boada, Aram Richarz, Nina Marcoval, Joaquim Ferreres, Josep Ramón Bodet, Domingo Martí, Rosa María Segura, Sonia Sabat, Mireia Dalmau, Joan Quintana, Mònica Azon, Antoni Curcó, Neus Formigon, Manel Olivella-Garcés, María Rosa Zaballos, Pedro Sola, Joaquim Galvany, Loida Baliu-Piqué, Carola Alegre, Marta Pasquali, Paola Malvehy, Josep Puig, Susana J Clin Med Article The incidence of melanoma has been increasing worldwide during recent decades. The objective of the study was to analyse the trends in incidence for in situ and invasive melanoma in the Spanish region of Catalonia during the period of 2008–2017. We designed a cross-sectional study with an age-period-cohort analysis of melanoma patient data from the Network of Melanoma Centres in Catalonia. Our database covered a population of over seven million and included a total of 8626 patients with incident melanoma. The main outcome measures were crude and age-standardised incidence rates to the European 2013 standard population. Joinpoint regression models were used to evaluate the population trends. We observed an increase in the age-standardised incidence rate (per 100,000 population) of all melanoma subtypes from 11.56 in 2008 to 13.78 in 2017 with an average annual percent change (AAPC) of 3.5%. This incidence increase was seen exclusively in the older population. Moreover, the stratified analysis showed a statistically significant increase in the age-standardised incidence rate for invasive (AAPC 2.1%) and in situ melanoma (AAPC 6.5%). In conclusion, the incidence of melanoma has continued to increase in the elderly population over recent decades, with a rapidly increasing trend of in situ melanomas and the lentigo maligna subtype. MDPI 2020-10-23 /pmc/articles/PMC7690683/ /pubmed/33113930 http://dx.doi.org/10.3390/jcm9113396 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Podlipnik, Sebastian
Carrera, Cristina
Boada, Aram
Richarz, Nina
Marcoval, Joaquim
Ferreres, Josep Ramón
Bodet, Domingo
Martí, Rosa María
Segura, Sonia
Sabat, Mireia
Dalmau, Joan
Quintana, Mònica
Azon, Antoni
Curcó, Neus
Formigon, Manel
Olivella-Garcés, María Rosa
Zaballos, Pedro
Sola, Joaquim
Galvany, Loida
Baliu-Piqué, Carola
Alegre, Marta
Pasquali, Paola
Malvehy, Josep
Puig, Susana
Incidence of Melanoma in Catalonia, Spain, Is Rapidly Increasing in the Elderly Population. A Multicentric Cohort Study
title Incidence of Melanoma in Catalonia, Spain, Is Rapidly Increasing in the Elderly Population. A Multicentric Cohort Study
title_full Incidence of Melanoma in Catalonia, Spain, Is Rapidly Increasing in the Elderly Population. A Multicentric Cohort Study
title_fullStr Incidence of Melanoma in Catalonia, Spain, Is Rapidly Increasing in the Elderly Population. A Multicentric Cohort Study
title_full_unstemmed Incidence of Melanoma in Catalonia, Spain, Is Rapidly Increasing in the Elderly Population. A Multicentric Cohort Study
title_short Incidence of Melanoma in Catalonia, Spain, Is Rapidly Increasing in the Elderly Population. A Multicentric Cohort Study
title_sort incidence of melanoma in catalonia, spain, is rapidly increasing in the elderly population. a multicentric cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690683/
https://www.ncbi.nlm.nih.gov/pubmed/33113930
http://dx.doi.org/10.3390/jcm9113396
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