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Towards resolving the enigma of the dichotomy of resveratrol: cis- and trans-resveratrol have opposite effects on TyrRS-regulated PARP1 activation

Unlike widely perceived, resveratrol (RSV) decreased the average lifespan and extended only the replicative lifespan in yeast. Similarly, although not widely discussed, RSV is also known to evoke neurite degeneration, kidney toxicity, atherosclerosis, premature senescence, and genotoxicity through y...

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Detalles Bibliográficos
Autores principales: Jhanji, Megha, Rao, Chintada Nageswara, Sajish, Mathew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690980/
https://www.ncbi.nlm.nih.gov/pubmed/33244652
http://dx.doi.org/10.1007/s11357-020-00295-w

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