Cargando…
Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature
Lupus aortitis is a rare and potentially life-threatening disorder. Previous studies have reported the utility of high-dose systemic glucocorticoids or surgery as the treatment, although there have been no related controlled trials. We herein report a 49-year-old woman with a 35-year history of syst...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691017/ https://www.ncbi.nlm.nih.gov/pubmed/32641654 http://dx.doi.org/10.2169/internalmedicine.4964-20 |
_version_ | 1783614198635298816 |
---|---|
author | Akebo, Hiroyuki Sada, Ryuichi Matsushita, Sho Ishimaru, Hiroyasu Minoda, Saki Miyake, Hirofumi Tsugihashi, Yukio Hatta, Kazuhiro |
author_facet | Akebo, Hiroyuki Sada, Ryuichi Matsushita, Sho Ishimaru, Hiroyasu Minoda, Saki Miyake, Hirofumi Tsugihashi, Yukio Hatta, Kazuhiro |
author_sort | Akebo, Hiroyuki |
collection | PubMed |
description | Lupus aortitis is a rare and potentially life-threatening disorder. Previous studies have reported the utility of high-dose systemic glucocorticoids or surgery as the treatment, although there have been no related controlled trials. We herein report a 49-year-old woman with a 35-year history of systemic lupus erythematosus who was diagnosed with aortitis. Her symptoms and laboratory and imaging abnormalities rapidly resolved upon the administration of moderate-dose glucocorticoids. We subsequently performed a literature review of similar cases to identify the appropriate treatment and discuss these cases. A study of further cases will be needed to identify the characteristics of patients who would benefit from moderate-dose glucocorticoid therapy. |
format | Online Article Text |
id | pubmed-7691017 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-76910172020-12-03 Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature Akebo, Hiroyuki Sada, Ryuichi Matsushita, Sho Ishimaru, Hiroyasu Minoda, Saki Miyake, Hirofumi Tsugihashi, Yukio Hatta, Kazuhiro Intern Med Case Report Lupus aortitis is a rare and potentially life-threatening disorder. Previous studies have reported the utility of high-dose systemic glucocorticoids or surgery as the treatment, although there have been no related controlled trials. We herein report a 49-year-old woman with a 35-year history of systemic lupus erythematosus who was diagnosed with aortitis. Her symptoms and laboratory and imaging abnormalities rapidly resolved upon the administration of moderate-dose glucocorticoids. We subsequently performed a literature review of similar cases to identify the appropriate treatment and discuss these cases. A study of further cases will be needed to identify the characteristics of patients who would benefit from moderate-dose glucocorticoid therapy. The Japanese Society of Internal Medicine 2020-07-07 2020-11-01 /pmc/articles/PMC7691017/ /pubmed/32641654 http://dx.doi.org/10.2169/internalmedicine.4964-20 Text en Copyright © 2020 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Akebo, Hiroyuki Sada, Ryuichi Matsushita, Sho Ishimaru, Hiroyasu Minoda, Saki Miyake, Hirofumi Tsugihashi, Yukio Hatta, Kazuhiro Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature |
title | Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature |
title_full | Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature |
title_fullStr | Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature |
title_full_unstemmed | Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature |
title_short | Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature |
title_sort | lupus aortitis successfully treated with moderate-dose glucocorticoids: a case report and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691017/ https://www.ncbi.nlm.nih.gov/pubmed/32641654 http://dx.doi.org/10.2169/internalmedicine.4964-20 |
work_keys_str_mv | AT akebohiroyuki lupusaortitissuccessfullytreatedwithmoderatedoseglucocorticoidsacasereportandreviewoftheliterature AT sadaryuichi lupusaortitissuccessfullytreatedwithmoderatedoseglucocorticoidsacasereportandreviewoftheliterature AT matsushitasho lupusaortitissuccessfullytreatedwithmoderatedoseglucocorticoidsacasereportandreviewoftheliterature AT ishimaruhiroyasu lupusaortitissuccessfullytreatedwithmoderatedoseglucocorticoidsacasereportandreviewoftheliterature AT minodasaki lupusaortitissuccessfullytreatedwithmoderatedoseglucocorticoidsacasereportandreviewoftheliterature AT miyakehirofumi lupusaortitissuccessfullytreatedwithmoderatedoseglucocorticoidsacasereportandreviewoftheliterature AT tsugihashiyukio lupusaortitissuccessfullytreatedwithmoderatedoseglucocorticoidsacasereportandreviewoftheliterature AT hattakazuhiro lupusaortitissuccessfullytreatedwithmoderatedoseglucocorticoidsacasereportandreviewoftheliterature |