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Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature

Lupus aortitis is a rare and potentially life-threatening disorder. Previous studies have reported the utility of high-dose systemic glucocorticoids or surgery as the treatment, although there have been no related controlled trials. We herein report a 49-year-old woman with a 35-year history of syst...

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Autores principales: Akebo, Hiroyuki, Sada, Ryuichi, Matsushita, Sho, Ishimaru, Hiroyasu, Minoda, Saki, Miyake, Hirofumi, Tsugihashi, Yukio, Hatta, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691017/
https://www.ncbi.nlm.nih.gov/pubmed/32641654
http://dx.doi.org/10.2169/internalmedicine.4964-20
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author Akebo, Hiroyuki
Sada, Ryuichi
Matsushita, Sho
Ishimaru, Hiroyasu
Minoda, Saki
Miyake, Hirofumi
Tsugihashi, Yukio
Hatta, Kazuhiro
author_facet Akebo, Hiroyuki
Sada, Ryuichi
Matsushita, Sho
Ishimaru, Hiroyasu
Minoda, Saki
Miyake, Hirofumi
Tsugihashi, Yukio
Hatta, Kazuhiro
author_sort Akebo, Hiroyuki
collection PubMed
description Lupus aortitis is a rare and potentially life-threatening disorder. Previous studies have reported the utility of high-dose systemic glucocorticoids or surgery as the treatment, although there have been no related controlled trials. We herein report a 49-year-old woman with a 35-year history of systemic lupus erythematosus who was diagnosed with aortitis. Her symptoms and laboratory and imaging abnormalities rapidly resolved upon the administration of moderate-dose glucocorticoids. We subsequently performed a literature review of similar cases to identify the appropriate treatment and discuss these cases. A study of further cases will be needed to identify the characteristics of patients who would benefit from moderate-dose glucocorticoid therapy.
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spelling pubmed-76910172020-12-03 Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature Akebo, Hiroyuki Sada, Ryuichi Matsushita, Sho Ishimaru, Hiroyasu Minoda, Saki Miyake, Hirofumi Tsugihashi, Yukio Hatta, Kazuhiro Intern Med Case Report Lupus aortitis is a rare and potentially life-threatening disorder. Previous studies have reported the utility of high-dose systemic glucocorticoids or surgery as the treatment, although there have been no related controlled trials. We herein report a 49-year-old woman with a 35-year history of systemic lupus erythematosus who was diagnosed with aortitis. Her symptoms and laboratory and imaging abnormalities rapidly resolved upon the administration of moderate-dose glucocorticoids. We subsequently performed a literature review of similar cases to identify the appropriate treatment and discuss these cases. A study of further cases will be needed to identify the characteristics of patients who would benefit from moderate-dose glucocorticoid therapy. The Japanese Society of Internal Medicine 2020-07-07 2020-11-01 /pmc/articles/PMC7691017/ /pubmed/32641654 http://dx.doi.org/10.2169/internalmedicine.4964-20 Text en Copyright © 2020 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Akebo, Hiroyuki
Sada, Ryuichi
Matsushita, Sho
Ishimaru, Hiroyasu
Minoda, Saki
Miyake, Hirofumi
Tsugihashi, Yukio
Hatta, Kazuhiro
Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature
title Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature
title_full Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature
title_fullStr Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature
title_full_unstemmed Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature
title_short Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature
title_sort lupus aortitis successfully treated with moderate-dose glucocorticoids: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691017/
https://www.ncbi.nlm.nih.gov/pubmed/32641654
http://dx.doi.org/10.2169/internalmedicine.4964-20
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