Cargando…
Flavonols as potential antiviral drugs targeting SARS-CoV-2 proteases (3CL(pro) and PL(pro)), spike protein, RNA-dependent RNA polymerase (RdRp) and angiotensin-converting enzyme II receptor (ACE2)
The novel coronavirus outbreak (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents the actual greatest global public health crisis. The lack of efficacious drugs and vaccines against this viral infection created a challenge for scientific researchers in order...
Autores principales: | Mouffouk, Chaima, Mouffouk, Soumia, Mouffouk, Sara, Hambaba, Leila, Haba, Hamada |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691142/ https://www.ncbi.nlm.nih.gov/pubmed/33249077 http://dx.doi.org/10.1016/j.ejphar.2020.173759 |
Ejemplares similares
-
In silico study of natural compounds from sesame against COVID-19 by targeting M(pro), PL(pro) and RdRp
por: Allam, Ahmed E., et al.
Publicado: (2021) -
RdRp or RT, That is the Question
por: Peyambari, Mahtab, et al.
Publicado: (2021) -
In silico investigation to identify potential small molecule inhibitors of the RNA-dependent RNA polymerase (RdRp) nidovirus RdRp-associated nucleotidyltransferase domain
por: Pitsillou, Eleni, et al.
Publicado: (2021) -
Virtual screening based on the structure of more than 10(5) compounds against four key proteins of SARS-CoV-2: M(Pro), S(RBD), RdRp, and PL(pro)
por: Nabati, Farzan, et al.
Publicado: (2022) -
Evaluation of potential anti-RNA-dependent RNA polymerase (RdRP) drugs against the newly emerged model of COVID-19 RdRP using computational methods
por: Poustforoosh, Alireza, et al.
Publicado: (2021)