Synovial Mesenchymal Stem Cell-Derived EV-Packaged miR-31 Downregulates Histone Demethylase KDM2A to Prevent Knee Osteoarthritis

Extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) have emerged as important mediators of intercellular communication in response to cartilage damage. In this study, we sought to characterize the inhibitory role of microRNA (miR)-31 encapsulated in synovial MSC (SMSC)-derived EV...

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Detalles Bibliográficos
Autores principales: Wang, Kunpeng, Li, Feng, Yuan, Yuan, Shan, Liang, Cui, Yong, Qu, Jing, Lian, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691165/
https://www.ncbi.nlm.nih.gov/pubmed/33294294
http://dx.doi.org/10.1016/j.omtn.2020.09.014

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