Cargando…

Monosegment ALPPS for bilateral colorectal liver metastasis - One is enough

Associated liver partition and portal vein ligation for staged hepatectomy – ALPPS – procedure emerged as an alternative to treat patients needing extensive hepatic resections, but with a small future liver remnant. Initially described using the left lateral segments as liver remnant, ALPPS has been...

Descripción completa

Detalles Bibliográficos
Autores principales: Steinbrück, Klaus, Fernandes, Reinaldo, Stoduto, Gustavo, Auel, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Hepato-Biliary-Pancreatic Surgery 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691201/
https://www.ncbi.nlm.nih.gov/pubmed/33234757
http://dx.doi.org/10.14701/ahbps.2020.24.4.522
_version_ 1783614238922637312
author Steinbrück, Klaus
Fernandes, Reinaldo
Stoduto, Gustavo
Auel, Thomas
author_facet Steinbrück, Klaus
Fernandes, Reinaldo
Stoduto, Gustavo
Auel, Thomas
author_sort Steinbrück, Klaus
collection PubMed
description Associated liver partition and portal vein ligation for staged hepatectomy – ALPPS – procedure emerged as an alternative to treat patients needing extensive hepatic resections, but with a small future liver remnant. Initially described using the left lateral segments as liver remnant, ALPPS has been adapted to leave as remainder only one segment. Describe a case of a patiente with bilobar colorectal liver metastasis submitted to segment 4-1 ALPPS. A 63-year-old man, previously submitted to transversostomy, due to a left colon stenosing adenocarcinoma, associated to bilobar liver metastasis, was referred for our evaluation, after receiving a FOLFOX based chemotherapy. Due to the large load of tumor within the liver, we opted to perform a segment 4-1 ALPPS, which was carried out with an interval of 21 days between first and second stages. The liver remnant increased from 250 cc to 694 cc (18% to 48% of standard liver volume). The patient was discharged 15 days after second stage surgery and was subjected to left colectomy after five months. He is disease-free ten months after liver surgery. Monosegment ALPPS is a challenging, but feasible procedure, that should be criteriously indicated in selected patients and performed by a hepatobiliary surgery team with experience in complex major hepatectomies.
format Online
Article
Text
id pubmed-7691201
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher The Korean Association of Hepato-Biliary-Pancreatic Surgery
record_format MEDLINE/PubMed
spelling pubmed-76912012020-12-08 Monosegment ALPPS for bilateral colorectal liver metastasis - One is enough Steinbrück, Klaus Fernandes, Reinaldo Stoduto, Gustavo Auel, Thomas Ann Hepatobiliary Pancreat Surg Case Report Associated liver partition and portal vein ligation for staged hepatectomy – ALPPS – procedure emerged as an alternative to treat patients needing extensive hepatic resections, but with a small future liver remnant. Initially described using the left lateral segments as liver remnant, ALPPS has been adapted to leave as remainder only one segment. Describe a case of a patiente with bilobar colorectal liver metastasis submitted to segment 4-1 ALPPS. A 63-year-old man, previously submitted to transversostomy, due to a left colon stenosing adenocarcinoma, associated to bilobar liver metastasis, was referred for our evaluation, after receiving a FOLFOX based chemotherapy. Due to the large load of tumor within the liver, we opted to perform a segment 4-1 ALPPS, which was carried out with an interval of 21 days between first and second stages. The liver remnant increased from 250 cc to 694 cc (18% to 48% of standard liver volume). The patient was discharged 15 days after second stage surgery and was subjected to left colectomy after five months. He is disease-free ten months after liver surgery. Monosegment ALPPS is a challenging, but feasible procedure, that should be criteriously indicated in selected patients and performed by a hepatobiliary surgery team with experience in complex major hepatectomies. The Korean Association of Hepato-Biliary-Pancreatic Surgery 2020-11-30 2020-11-30 /pmc/articles/PMC7691201/ /pubmed/33234757 http://dx.doi.org/10.14701/ahbps.2020.24.4.522 Text en Copyright © 2020 by The Korean Association of Hepato-Biliary-Pancreatic Surgery This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Steinbrück, Klaus
Fernandes, Reinaldo
Stoduto, Gustavo
Auel, Thomas
Monosegment ALPPS for bilateral colorectal liver metastasis - One is enough
title Monosegment ALPPS for bilateral colorectal liver metastasis - One is enough
title_full Monosegment ALPPS for bilateral colorectal liver metastasis - One is enough
title_fullStr Monosegment ALPPS for bilateral colorectal liver metastasis - One is enough
title_full_unstemmed Monosegment ALPPS for bilateral colorectal liver metastasis - One is enough
title_short Monosegment ALPPS for bilateral colorectal liver metastasis - One is enough
title_sort monosegment alpps for bilateral colorectal liver metastasis - one is enough
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691201/
https://www.ncbi.nlm.nih.gov/pubmed/33234757
http://dx.doi.org/10.14701/ahbps.2020.24.4.522
work_keys_str_mv AT steinbruckklaus monosegmentalppsforbilateralcolorectallivermetastasisoneisenough
AT fernandesreinaldo monosegmentalppsforbilateralcolorectallivermetastasisoneisenough
AT stodutogustavo monosegmentalppsforbilateralcolorectallivermetastasisoneisenough
AT auelthomas monosegmentalppsforbilateralcolorectallivermetastasisoneisenough