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Pediatric liver transplantation with hyperreduced left lateral segment graft
BACKGROUNDS/AIMS: To prevent large-for-size graft-related complications in small infant patients, the size of a left lateral segment (LLS) graft can be reduced to be a hyperreduced LLS (HRLLS) graft. METHODS: This study was intended to describe the detailed techniques for harvesting and implanting H...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Hepato-Biliary-Pancreatic Surgery
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691208/ https://www.ncbi.nlm.nih.gov/pubmed/33234754 http://dx.doi.org/10.14701/ahbps.2020.24.4.503 |
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author | Namgoong, Jung-Man Hwang, Shin Song, Gi-Won Kim, Dae-Yeon Ha, Tae-Yong Jung, Dong-Hwan Park, Gil-Chun Ahn, Chul-Soo Kim, Kyung Mo Oh, Seak Hee Kwon, Hyunhee Kwon, Yong Jae |
author_facet | Namgoong, Jung-Man Hwang, Shin Song, Gi-Won Kim, Dae-Yeon Ha, Tae-Yong Jung, Dong-Hwan Park, Gil-Chun Ahn, Chul-Soo Kim, Kyung Mo Oh, Seak Hee Kwon, Hyunhee Kwon, Yong Jae |
author_sort | Namgoong, Jung-Man |
collection | PubMed |
description | BACKGROUNDS/AIMS: To prevent large-for-size graft-related complications in small infant patients, the size of a left lateral segment (LLS) graft can be reduced to be a hyperreduced LLS (HRLLS) graft. METHODS: This study was intended to describe the detailed techniques for harvesting and implanting HRLLS grafts developed in a high-volume liver transplantation (LT) center. RESULTS: The mean recipient age was 4.0±1.7 months (range: 3-6) and body weight was 5.3±1.4 kg (range: 4.1-6.9). Primary diagnoses of the recipients were progressive familial intrahepatic cholestasis in 2 and biliary atresia in 1. The types of LT were living donor LT in 1 and split deceased donor LT in 2. Non-anatomical size reduction was performed to the transected LLS grafts. The mean weight of the HRLLS grafts was 191.7±62.1 g (range: 120-230) and graft-recipient weight ratio was 3.75±1.57% (range: 2.45-5.49). Widening venoplasty was applied to the graft left hepatic vein outflow orifice. Vein homograft interposition was used in a case with portal vein hypoplasia. Types of the abdomen wound closure were one case of primary repair, one of two-staged closure with a mesh, and one of three-staged repair with a silo and a mesh. All three patients recovered uneventfully from the LT operation and are doing well to date for more than 6 years after transplantation. CONCLUSIONS: Making a HRLLS graft through non-anatomical resection during living donor LT and split deceased donor LT can be a useful option for treating small infant patients. |
format | Online Article Text |
id | pubmed-7691208 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Korean Association of Hepato-Biliary-Pancreatic Surgery |
record_format | MEDLINE/PubMed |
spelling | pubmed-76912082020-12-08 Pediatric liver transplantation with hyperreduced left lateral segment graft Namgoong, Jung-Man Hwang, Shin Song, Gi-Won Kim, Dae-Yeon Ha, Tae-Yong Jung, Dong-Hwan Park, Gil-Chun Ahn, Chul-Soo Kim, Kyung Mo Oh, Seak Hee Kwon, Hyunhee Kwon, Yong Jae Ann Hepatobiliary Pancreat Surg How-I-Do-It BACKGROUNDS/AIMS: To prevent large-for-size graft-related complications in small infant patients, the size of a left lateral segment (LLS) graft can be reduced to be a hyperreduced LLS (HRLLS) graft. METHODS: This study was intended to describe the detailed techniques for harvesting and implanting HRLLS grafts developed in a high-volume liver transplantation (LT) center. RESULTS: The mean recipient age was 4.0±1.7 months (range: 3-6) and body weight was 5.3±1.4 kg (range: 4.1-6.9). Primary diagnoses of the recipients were progressive familial intrahepatic cholestasis in 2 and biliary atresia in 1. The types of LT were living donor LT in 1 and split deceased donor LT in 2. Non-anatomical size reduction was performed to the transected LLS grafts. The mean weight of the HRLLS grafts was 191.7±62.1 g (range: 120-230) and graft-recipient weight ratio was 3.75±1.57% (range: 2.45-5.49). Widening venoplasty was applied to the graft left hepatic vein outflow orifice. Vein homograft interposition was used in a case with portal vein hypoplasia. Types of the abdomen wound closure were one case of primary repair, one of two-staged closure with a mesh, and one of three-staged repair with a silo and a mesh. All three patients recovered uneventfully from the LT operation and are doing well to date for more than 6 years after transplantation. CONCLUSIONS: Making a HRLLS graft through non-anatomical resection during living donor LT and split deceased donor LT can be a useful option for treating small infant patients. The Korean Association of Hepato-Biliary-Pancreatic Surgery 2020-11-30 2020-11-30 /pmc/articles/PMC7691208/ /pubmed/33234754 http://dx.doi.org/10.14701/ahbps.2020.24.4.503 Text en Copyright © 2020 by The Korean Association of Hepato-Biliary-Pancreatic Surgery This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | How-I-Do-It Namgoong, Jung-Man Hwang, Shin Song, Gi-Won Kim, Dae-Yeon Ha, Tae-Yong Jung, Dong-Hwan Park, Gil-Chun Ahn, Chul-Soo Kim, Kyung Mo Oh, Seak Hee Kwon, Hyunhee Kwon, Yong Jae Pediatric liver transplantation with hyperreduced left lateral segment graft |
title | Pediatric liver transplantation with hyperreduced left lateral segment graft |
title_full | Pediatric liver transplantation with hyperreduced left lateral segment graft |
title_fullStr | Pediatric liver transplantation with hyperreduced left lateral segment graft |
title_full_unstemmed | Pediatric liver transplantation with hyperreduced left lateral segment graft |
title_short | Pediatric liver transplantation with hyperreduced left lateral segment graft |
title_sort | pediatric liver transplantation with hyperreduced left lateral segment graft |
topic | How-I-Do-It |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691208/ https://www.ncbi.nlm.nih.gov/pubmed/33234754 http://dx.doi.org/10.14701/ahbps.2020.24.4.503 |
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