Transcatheter-Delivered Expandable Bioresorbable Polymeric Graft With Stenting Capacity Induces Vascular Regeneration

As the next step in the translation of vascular tissue engineering, this study uniquely combines transcatheter delivery and in situ tissue regeneration using a novel bioresorbable electrospun polymer graft that can be implanted minimally invasively. Once delivered inside a small-diameter vessel, the...

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Detalles Bibliográficos
Autores principales: Duijvelshoff, Renee, Cabrera, Maria S., Sanders, Bart, Dekker, Sylvia, Smits, Anthal I.P.M., Baaijens, Frank P.T., Bouten, Carlijn V.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Preclinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691284/
https://www.ncbi.nlm.nih.gov/pubmed/33294741
http://dx.doi.org/10.1016/j.jacbts.2020.09.005
Descripción
Sumario:As the next step in the translation of vascular tissue engineering, this study uniquely combines transcatheter delivery and in situ tissue regeneration using a novel bioresorbable electrospun polymer graft that can be implanted minimally invasively. Once delivered inside a small-diameter vessel, the electrospun microstructure supports the vessel wall, facilitates cellular infiltration, and guides organized tissue formation.

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