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Empowering alcohols as carbonyl surrogates for Grignard-type reactions

The Grignard reaction is a fundamental tool for constructing C-C bonds. Although it is widely used in synthetic chemistry, it is normally applied in early stage functionalizations owing to poor functional group tolerance and less availability of carbonyls at late stages of molecular modifications. H...

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Detalles Bibliográficos
Autores principales: Li, Chen-Chen, Wang, Haining, Sim, Malcolm M., Qiu, Zihang, Chen, Zhang-Pei, Khaliullin, Rustam Z., Li, Chao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691337/
https://www.ncbi.nlm.nih.gov/pubmed/33244009
http://dx.doi.org/10.1038/s41467-020-19857-9

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