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Empowering alcohols as carbonyl surrogates for Grignard-type reactions
The Grignard reaction is a fundamental tool for constructing C-C bonds. Although it is widely used in synthetic chemistry, it is normally applied in early stage functionalizations owing to poor functional group tolerance and less availability of carbonyls at late stages of molecular modifications. H...
Autores principales: | Li, Chen-Chen, Wang, Haining, Sim, Malcolm M., Qiu, Zihang, Chen, Zhang-Pei, Khaliullin, Rustam Z., Li, Chao-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691337/ https://www.ncbi.nlm.nih.gov/pubmed/33244009 http://dx.doi.org/10.1038/s41467-020-19857-9 |
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