Cargando…
Maternal DOT1L is dispensable for mouse development
A battery of chromatin modifying enzymes play essential roles in remodeling the epigenome in the zygote and cleavage stage embryos, when the maternal genome is the sole contributor. Here we identify an exemption. DOT1L methylates lysine 79 in the globular domain of histone H3 (H3K79). Dot1l is an es...
Autores principales: | Liao, Ji, Szabó, Piroska E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691351/ https://www.ncbi.nlm.nih.gov/pubmed/33244015 http://dx.doi.org/10.1038/s41598-020-77545-6 |
Ejemplares similares
-
Hotair Is Dispensible for Mouse Development
por: Amândio, Ana Rita, et al.
Publicado: (2016) -
Comment on "Hotair Is Dispensable for Mouse Development"
por: Li, Lingjie, et al.
Publicado: (2016) -
Twinfilin-2a Is Dispensable for Mouse Development
por: Nevalainen, Elisa M., et al.
Publicado: (2011) -
EHMT2 suppresses the variation of transcriptional switches in the mouse embryo
por: Zeng, Tie-Bo, et al.
Publicado: (2021) -
Maternal TET3 is dispensable for embryonic development but is required for neonatal growth
por: Tsukada, Yu-ichi, et al.
Publicado: (2015)