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Excavating the functionally crucial active-site residues of the DXS protein of Bacillus subtilis by exploring its closest homologues
BACKGROUND: To achieve a high yield of terpenoid-based therapeutics, 1-deoxy-d-xylulose-5-phosphate (DXP) pathway has been significantly exploited for the production of downstream enzymes. The DXP synthase (DXS) enzyme, the initiator of this pathway, is pivotal for the convergence of carbon flux, an...
Autores principales: | Runthala, Ashish, Sai, Tavakala Harsha, Kamjula, Vandana, Phulara, Suresh C., Rajput, Vikrant Singh, Sangapillai, Karthikeyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691408/ https://www.ncbi.nlm.nih.gov/pubmed/33242110 http://dx.doi.org/10.1186/s43141-020-00087-x |
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