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Acid- and Volume-Sensitive Chloride Currents in Human Chondrocytes
Chondrocytes face extreme alterations of extracellular osmolarity and pH, which force them to appropriately regulate their cell volume (CV) and cellular pH. Perturbations of these mechanisms lead to chondrocyte death and ultimately to osteoarthritis (OA), the most common chronic joint diseases world...
Autores principales: | Kittl, Michael, Winklmayr, Martina, Helm, Katharina, Lettner, Johannes, Gaisberger, Martin, Ritter, Markus, Jakab, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691427/ https://www.ncbi.nlm.nih.gov/pubmed/33282866 http://dx.doi.org/10.3389/fcell.2020.583131 |
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