Combined TCR Repertoire Profiles and Blood Cell Phenotypes Predict Melanoma Patient Response to Personalized Neoantigen Therapy plus Anti-PD-1

T cells use highly diverse receptors (TCRs) to identify tumor cells presenting neoantigens arising from genetic mutations and establish anti-tumor activity. Immunotherapy harnessing neoantigen-specific T cells to target tumors has emerged as a promising clinical approach. To assess whether a compreh...

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Detalles Bibliográficos
Autores principales: Poran, Asaf, Scherer, Julian, Bushway, Meghan E., Besada, Rana, Balogh, Kristen N., Wanamaker, Amy, Williams, Reid G., Prabhakara, Jasmina, Ott, Patrick A., Hu-Lieskovan, Siwen, Khondker, Zakaria S., Gaynor, Richard B., Rooney, Michael S., Srinivasan, Lakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691446/
https://www.ncbi.nlm.nih.gov/pubmed/33294862
http://dx.doi.org/10.1016/j.xcrm.2020.100141

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