Cargando…
Collagen production and niche engineering: A novel strategy for cancer cells to survive acidosis in DCIS and evolve
Growing tumors are dynamic and nonlinear ecosystems, wherein cancer cells adapt to their local microenvironment, and these adaptations further modify the environment, inducing more changes. From nascent intraductal neoplasms to disseminated metastatic disease, several levels of evolutionary adaptati...
Autores principales: | Damaghi, Mehdi, Mori, Hidetoshi, Byrne, Samantha, Xu, Liping, Chen, Tingan, Johnson, Joseph, Gallant, Nathan D., Marusyk, Andriy, Borowsky, Alexander D., Gillies, Robert J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691473/ https://www.ncbi.nlm.nih.gov/pubmed/33294017 http://dx.doi.org/10.1111/eva.13075 |
Ejemplares similares
-
Glucose Uptake and Intracellular pH in a Mouse Model of Ductal Carcinoma In situ (DCIS) Suggests Metabolic Heterogeneity
por: Lobo, Rebecca C., et al.
Publicado: (2016) -
Targeting of Evolutionarily Acquired Cancer Cell Phenotype by Exploiting pHi-Metabolic Vulnerabilities
por: Ordway, Bryce, et al.
Publicado: (2020) -
Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane
por: Damaghi, Mehdi, et al.
Publicado: (2015) -
Is palpable DCIS more aggressive than screen-detected DCIS?
por: Balac, Nina, et al.
Publicado: (2022) -
Extracellular Acidification Induces Lysosomal Dysregulation
por: Ordway, Bryce, et al.
Publicado: (2021)