The absence of (TCAGGG)(n) repeats in some telomeres, combined with variable responses to NR2F2 depletion, suggest that this nuclear receptor plays an indirect role in the alternative lengthening of telomeres

The alternative lengthening of telomeres (ALT) facilitates telomere lengthening by a DNA strand invasion and copying mechanism. The nuclear receptors (NRs), NR2F2 and NR2C2, can bind to (TCAGGG)(n) variant repeats within telomeres and it has been proposed that this facilitates telomere interactions...

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Detalles Bibliográficos
Autores principales: Alhendi, Ahmed S. N., Royle, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691514/
https://www.ncbi.nlm.nih.gov/pubmed/33244044
http://dx.doi.org/10.1038/s41598-020-77606-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691514/
https://www.ncbi.nlm.nih.gov/pubmed/33244044
http://dx.doi.org/10.1038/s41598-020-77606-w

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