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Insulin and obesity transform hypothalamic-pituitary-adrenal axis stemness and function in a hyperactive state
OBJECTIVE: Metabolic diseases are an increasing problem in society with the brain-metabolic axis as a master regulator of the human body for sustaining homeostasis under metabolic stress. However, metabolic inflammation and disease will trigger sustained activation of the hypothalamic-pituitary-adre...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691554/ https://www.ncbi.nlm.nih.gov/pubmed/33157254 http://dx.doi.org/10.1016/j.molmet.2020.101112 |