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Insulin and obesity transform hypothalamic-pituitary-adrenal axis stemness and function in a hyperactive state

OBJECTIVE: Metabolic diseases are an increasing problem in society with the brain-metabolic axis as a master regulator of the human body for sustaining homeostasis under metabolic stress. However, metabolic inflammation and disease will trigger sustained activation of the hypothalamic-pituitary-adre...

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Detalles Bibliográficos
Autores principales: Werdermann, Martin, Berger, Ilona, Scriba, Laura D., Santambrogio, Alice, Schlinkert, Pia, Brendel, Heike, Morawietz, Henning, Schedl, Andreas, Peitzsch, Mirko, King, Aileen J.F., Andoniadou, Cynthia L., Bornstein, Stefan R., Steenblock, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691554/
https://www.ncbi.nlm.nih.gov/pubmed/33157254
http://dx.doi.org/10.1016/j.molmet.2020.101112

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