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Development and Validation of a Mathematical Model to Predict the Complexity of FMR1 Allele Combinations

The polymorphic trinucleotide repetitive region in the FMR1 gene 5′UTR contains AGG interspersions, particularly in normal-sized alleles (CGG < 45). In this range repetitive stretches are typically interrupted once or twice, although alleles without or with three or more AGG interspersions can al...

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Detalles Bibliográficos
Autores principales:	Rodrigues, Bárbara, Vale-Fernandes, Emídio, Maia, Nuno, Santos, Flávia, Marques, Isabel, Santos, Rosário, Nogueira, António J. A., Jorge, Paula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691586/ https://www.ncbi.nlm.nih.gov/pubmed/33281866 http://dx.doi.org/10.3389/fgene.2020.557147

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