The m(6)A reader YTHDC2 inhibits lung adenocarcinoma tumorigenesis by suppressing SLC7A11-dependent antioxidant function

The biological functions of N6-methyladenosine (m(6)A) RNA methylation are mainly dependent on the reader; however, its role in lung tumorigenesis remains unclear. Here, we have demonstrated that the m(6)A reader YT521-B homology domain containing 2 (YTHDC2) is frequently suppressed in lung adenocar...

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Detalles Bibliográficos
Autores principales: Ma, Lifang, Chen, Tianxiang, Zhang, Xiao, Miao, Yayou, Tian, Xiaoting, Yu, Keke, Xu, Xin, Niu, Yongjie, Guo, Susu, Zhang, Congcong, Qiu, Shiyu, Qiao, Yongxia, Fang, Wentao, Du, Lutao, Yu, Yongchun, Wang, Jiayi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691619/
https://www.ncbi.nlm.nih.gov/pubmed/33232910
http://dx.doi.org/10.1016/j.redox.2020.101801

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