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Necrotizing Skin Findings in Coronavirus Disease 2019: A Case Report

Coronavirus is a single-stranded RNA virus that causes acute respiratory syndrome and various skin lesions. In addition, ischemic acral lesions have been reported in patients with severe coronavirus disease 2019 (COVID-19) due to coagulation disorders. We here present a case with ischemic acral lesi...

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Detalles Bibliográficos
Autores principales: Çabuk, Fatmagül Kuşku, Sakiz, Damlanur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Society of Pathology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691707/
https://www.ncbi.nlm.nih.gov/pubmed/33391385
http://dx.doi.org/10.30699/ijp.2020.128904.2408
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author Çabuk, Fatmagül Kuşku
Sakiz, Damlanur
author_facet Çabuk, Fatmagül Kuşku
Sakiz, Damlanur
author_sort Çabuk, Fatmagül Kuşku
collection PubMed
description Coronavirus is a single-stranded RNA virus that causes acute respiratory syndrome and various skin lesions. In addition, ischemic acral lesions have been reported in patients with severe coronavirus disease 2019 (COVID-19) due to coagulation disorders. We here present a case with ischemic acral lesions caused by COVID-19. The patient was 51-year old male who was hospitalized with COVID-19 pneumonia. After 28 days in the Intensive Care Unit, patient developed acroischemic lesions in the fingers and toes. In the histopathologic examination, vasculitis was observed as the infiltration of mixed-type inflammatory cells in the mid-sized muscular arteries wall. Moreover, microthrombosis was detected in small capillaries. It is clear that thrombotic lesions have occurred as a result of COVID-19 or administered treatment. Further studies are required to confirm and better characterize the skin reactions in COVID-19.
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spelling pubmed-76917072021-01-01 Necrotizing Skin Findings in Coronavirus Disease 2019: A Case Report Çabuk, Fatmagül Kuşku Sakiz, Damlanur Iran J Pathol Case Report Coronavirus is a single-stranded RNA virus that causes acute respiratory syndrome and various skin lesions. In addition, ischemic acral lesions have been reported in patients with severe coronavirus disease 2019 (COVID-19) due to coagulation disorders. We here present a case with ischemic acral lesions caused by COVID-19. The patient was 51-year old male who was hospitalized with COVID-19 pneumonia. After 28 days in the Intensive Care Unit, patient developed acroischemic lesions in the fingers and toes. In the histopathologic examination, vasculitis was observed as the infiltration of mixed-type inflammatory cells in the mid-sized muscular arteries wall. Moreover, microthrombosis was detected in small capillaries. It is clear that thrombotic lesions have occurred as a result of COVID-19 or administered treatment. Further studies are required to confirm and better characterize the skin reactions in COVID-19. Iranian Society of Pathology 2021 2020-10-10 /pmc/articles/PMC7691707/ /pubmed/33391385 http://dx.doi.org/10.30699/ijp.2020.128904.2408 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Çabuk, Fatmagül Kuşku
Sakiz, Damlanur
Necrotizing Skin Findings in Coronavirus Disease 2019: A Case Report
title Necrotizing Skin Findings in Coronavirus Disease 2019: A Case Report
title_full Necrotizing Skin Findings in Coronavirus Disease 2019: A Case Report
title_fullStr Necrotizing Skin Findings in Coronavirus Disease 2019: A Case Report
title_full_unstemmed Necrotizing Skin Findings in Coronavirus Disease 2019: A Case Report
title_short Necrotizing Skin Findings in Coronavirus Disease 2019: A Case Report
title_sort necrotizing skin findings in coronavirus disease 2019: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691707/
https://www.ncbi.nlm.nih.gov/pubmed/33391385
http://dx.doi.org/10.30699/ijp.2020.128904.2408
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