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Retinal Spheroids and Axon Pathology Identified in Amyotrophic Lateral Sclerosis

PURPOSE: To determine whether patients with amyotrophic lateral sclerosis (ALS) show retinal axon pathology. METHODS: Postmortem eyes from 10 patients with ALS were sectioned and compared with 10 age-matched controls. Retinal sections were evaluated with periodic acid Schiff and phosphorylated (P-NF...

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Detalles Bibliográficos
Autores principales: Sharma, Kieran, Amin Mohammed Amin, Maryam, Gupta, Neeru, Zinman, Lorne, Zhou, Xun, Irving, Hyacinth, Yücel, Yeni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691787/
https://www.ncbi.nlm.nih.gov/pubmed/33226405
http://dx.doi.org/10.1167/iovs.61.13.30