RasV12 Expression in Microglia Initiates Retinal Inflammation and Induces Photoreceptor Degeneration

PURPOSE: The role of activated retinal microglia in driving retinal degeneration has been implicated in a number of in vivo disease models. Here, we investigated the primary consequences of microglial activation by the specific expression of constitutively active Ras in microglia in a transgenic mou...

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Detalles Bibliográficos
Autores principales: Moriuchi, Yuta, Iwagawa, Toshiro, Tsuhako, Asano, Koso, Hideto, Fujita, Yasuyuki, Watanabe, Sumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691791/
https://www.ncbi.nlm.nih.gov/pubmed/33231622
http://dx.doi.org/10.1167/iovs.61.13.34

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691791/
https://www.ncbi.nlm.nih.gov/pubmed/33231622
http://dx.doi.org/10.1167/iovs.61.13.34

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