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Can preprocedural mouthrinses reduce SARS-CoV-2 load in dental aerosols?

Dental professionals work closely with patients and present an increased risk of person-to-person transmission of SARS-CoV-2. Moreover, the use of ultrasonic scalers, air–water syringes, and slow and high-speed handpieces, which are common in the dental office, generate spatter and aerosol. The use...

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Autores principales: Reis, Isabella Neme Ribeiro, do Amaral, Guilherme Castro Lima Silva, Mendoza, Aldrin André Huamán, das Graças, Yasmin Teixeira, Mendes-Correa, Maria Cássia, Romito, Giuseppe Alexandre, Pannuti, Claudio Mendes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691843/
https://www.ncbi.nlm.nih.gov/pubmed/33288313
http://dx.doi.org/10.1016/j.mehy.2020.110436
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author Reis, Isabella Neme Ribeiro
do Amaral, Guilherme Castro Lima Silva
Mendoza, Aldrin André Huamán
das Graças, Yasmin Teixeira
Mendes-Correa, Maria Cássia
Romito, Giuseppe Alexandre
Pannuti, Claudio Mendes
author_facet Reis, Isabella Neme Ribeiro
do Amaral, Guilherme Castro Lima Silva
Mendoza, Aldrin André Huamán
das Graças, Yasmin Teixeira
Mendes-Correa, Maria Cássia
Romito, Giuseppe Alexandre
Pannuti, Claudio Mendes
author_sort Reis, Isabella Neme Ribeiro
collection PubMed
description Dental professionals work closely with patients and present an increased risk of person-to-person transmission of SARS-CoV-2. Moreover, the use of ultrasonic scalers, air–water syringes, and slow and high-speed handpieces, which are common in the dental office, generate spatter and aerosol. The use of preprocedural mouthrinses has been proposed to reduce the viral load in saliva and oropharyngeal tissues, thus decreasing viral load in dental aerosol. Although some mouthrinses demonstrates an antiviral effect, there is limited evidence about the clinical efficacy of any mouthrinse in the reduction of SARS-CoV-2 in the dental aerosol. We hypothesized that mouthrinses may reduce SARS-CoV-2 viral load in the oropharynx and its fluids reducing viral load in dental aerosol. The potential use of mouthrinses is discussed, along with proposal of in vitro and clinical studies, in order to evaluate this hypothesis. If this hypothesis holds true, dental professionals and patients may benefit from the routine use of preprocedural mouthrinses.
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spelling pubmed-76918432020-11-27 Can preprocedural mouthrinses reduce SARS-CoV-2 load in dental aerosols? Reis, Isabella Neme Ribeiro do Amaral, Guilherme Castro Lima Silva Mendoza, Aldrin André Huamán das Graças, Yasmin Teixeira Mendes-Correa, Maria Cássia Romito, Giuseppe Alexandre Pannuti, Claudio Mendes Med Hypotheses Article Dental professionals work closely with patients and present an increased risk of person-to-person transmission of SARS-CoV-2. Moreover, the use of ultrasonic scalers, air–water syringes, and slow and high-speed handpieces, which are common in the dental office, generate spatter and aerosol. The use of preprocedural mouthrinses has been proposed to reduce the viral load in saliva and oropharyngeal tissues, thus decreasing viral load in dental aerosol. Although some mouthrinses demonstrates an antiviral effect, there is limited evidence about the clinical efficacy of any mouthrinse in the reduction of SARS-CoV-2 in the dental aerosol. We hypothesized that mouthrinses may reduce SARS-CoV-2 viral load in the oropharynx and its fluids reducing viral load in dental aerosol. The potential use of mouthrinses is discussed, along with proposal of in vitro and clinical studies, in order to evaluate this hypothesis. If this hypothesis holds true, dental professionals and patients may benefit from the routine use of preprocedural mouthrinses. Elsevier Ltd. 2021-01 2020-11-27 /pmc/articles/PMC7691843/ /pubmed/33288313 http://dx.doi.org/10.1016/j.mehy.2020.110436 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Reis, Isabella Neme Ribeiro
do Amaral, Guilherme Castro Lima Silva
Mendoza, Aldrin André Huamán
das Graças, Yasmin Teixeira
Mendes-Correa, Maria Cássia
Romito, Giuseppe Alexandre
Pannuti, Claudio Mendes
Can preprocedural mouthrinses reduce SARS-CoV-2 load in dental aerosols?
title Can preprocedural mouthrinses reduce SARS-CoV-2 load in dental aerosols?
title_full Can preprocedural mouthrinses reduce SARS-CoV-2 load in dental aerosols?
title_fullStr Can preprocedural mouthrinses reduce SARS-CoV-2 load in dental aerosols?
title_full_unstemmed Can preprocedural mouthrinses reduce SARS-CoV-2 load in dental aerosols?
title_short Can preprocedural mouthrinses reduce SARS-CoV-2 load in dental aerosols?
title_sort can preprocedural mouthrinses reduce sars-cov-2 load in dental aerosols?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691843/
https://www.ncbi.nlm.nih.gov/pubmed/33288313
http://dx.doi.org/10.1016/j.mehy.2020.110436
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