Cnp Promoter-Driven Sustained ERK1/2 Activation Increases B-Cell Activation and Suppresses Experimental Autoimmune Encephalomyelitis

The ERK1/2 signaling pathway promotes myelin wrapping during development and remyelination, and sustained ERK1/2 activation in the oligodendrocyte (OL) lineage results in hypermyelination of the CNS. We therefore hypothesized that increased ERK1/2 signaling in the OL lineage would 1) protect against...

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Detalles Bibliográficos
Autores principales: Jeffries, Marisa A., Obr, Alison E., Urbanek, Kelly, Fyffe-Maricich, Sharyl L., Wood, Teresa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691909/
https://www.ncbi.nlm.nih.gov/pubmed/33228381
http://dx.doi.org/10.1177/1759091420971916

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