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“Open Sesame?”: Biomarker Status of the Human Equilibrative Nucleoside Transporter-1 and Molecular Mechanisms Influencing its Expression and Activity in the Uptake and Cytotoxicity of Gemcitabine in Pancreatic Cancer

SIMPLE SUMMARY: Despite the enormous advance in biomarker discovery, many potential biomarkers of drug activity are unable to satisfy the clinical need due to inadequate sensitivity and specificity. The nucleoside transporter hENT-1 has been studied as a potential biomarker to predict the effect of...

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Detalles Bibliográficos
Autores principales:	Randazzo, Ornella, Papini, Filippo, Mantini, Giulia, Gregori, Alessandro, Parrino, Barbara, Liu, Daniel S. K., Cascioferro, Stella, Carbone, Daniela, Peters, Godefridus J., Frampton, Adam E., Garajova, Ingrid, Giovannetti, Elisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692081/ https://www.ncbi.nlm.nih.gov/pubmed/33142664 http://dx.doi.org/10.3390/cancers12113206

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