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Poly(N,N′-Diethylacrylamide)-Based Thermoresponsive Hydrogels with Double Network Structure

Temperature response of double network (DN) hydrogels composed of thermoresponsive poly(N,N′-diethylacrylamide) (PDEAAm) and hydrophilic polyacrylamide (PAAm) or poly(N,N′-dimethylacrylamide) (PDMAAm) was studied by a combination of swelling measurements, differential scanning calorimetry (DSC) and...

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Autores principales: Hanyková, Lenka, Krakovský, Ivan, Šestáková, Eliška, Šťastná, Julie, Labuta, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692105/
https://www.ncbi.nlm.nih.gov/pubmed/33121186
http://dx.doi.org/10.3390/polym12112502
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author Hanyková, Lenka
Krakovský, Ivan
Šestáková, Eliška
Šťastná, Julie
Labuta, Jan
author_facet Hanyková, Lenka
Krakovský, Ivan
Šestáková, Eliška
Šťastná, Julie
Labuta, Jan
author_sort Hanyková, Lenka
collection PubMed
description Temperature response of double network (DN) hydrogels composed of thermoresponsive poly(N,N′-diethylacrylamide) (PDEAAm) and hydrophilic polyacrylamide (PAAm) or poly(N,N′-dimethylacrylamide) (PDMAAm) was studied by a combination of swelling measurements, differential scanning calorimetry (DSC) and (1)H NMR and UV-Vis spectroscopies. Presence of the second hydrophilic network in DN hydrogels influenced their thermal sensitivity significantly. DN hydrogels show less intensive changes in deswelling, smaller enthalpy, and entropy changes connected with phase transition and broader temperature interval of the transition than the single network (SN) hydrogels. Above the transition, the DN hydrogels contain significantly more permanently bound water in comparison with SN hydrogels due to interaction of water with the hydrophilic component. Unlike swelling and DSC experiments, a rather abrupt transition was revealed from temperature-dependent NMR spectra. Release study showed that model methylene blue molecules are released from SN and DN hydrogels within different time scale. New thermodynamical model of deswelling behaviour based on the approach of the van’t Hoff analysis was developed. The model allows to determine thermodynamic parameters connected with temperature-induced volume transition, such as the standard change of enthalpy and entropy and critical temperatures and characterize the structurally different states of water.
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spelling pubmed-76921052020-11-28 Poly(N,N′-Diethylacrylamide)-Based Thermoresponsive Hydrogels with Double Network Structure Hanyková, Lenka Krakovský, Ivan Šestáková, Eliška Šťastná, Julie Labuta, Jan Polymers (Basel) Article Temperature response of double network (DN) hydrogels composed of thermoresponsive poly(N,N′-diethylacrylamide) (PDEAAm) and hydrophilic polyacrylamide (PAAm) or poly(N,N′-dimethylacrylamide) (PDMAAm) was studied by a combination of swelling measurements, differential scanning calorimetry (DSC) and (1)H NMR and UV-Vis spectroscopies. Presence of the second hydrophilic network in DN hydrogels influenced their thermal sensitivity significantly. DN hydrogels show less intensive changes in deswelling, smaller enthalpy, and entropy changes connected with phase transition and broader temperature interval of the transition than the single network (SN) hydrogels. Above the transition, the DN hydrogels contain significantly more permanently bound water in comparison with SN hydrogels due to interaction of water with the hydrophilic component. Unlike swelling and DSC experiments, a rather abrupt transition was revealed from temperature-dependent NMR spectra. Release study showed that model methylene blue molecules are released from SN and DN hydrogels within different time scale. New thermodynamical model of deswelling behaviour based on the approach of the van’t Hoff analysis was developed. The model allows to determine thermodynamic parameters connected with temperature-induced volume transition, such as the standard change of enthalpy and entropy and critical temperatures and characterize the structurally different states of water. MDPI 2020-10-27 /pmc/articles/PMC7692105/ /pubmed/33121186 http://dx.doi.org/10.3390/polym12112502 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hanyková, Lenka
Krakovský, Ivan
Šestáková, Eliška
Šťastná, Julie
Labuta, Jan
Poly(N,N′-Diethylacrylamide)-Based Thermoresponsive Hydrogels with Double Network Structure
title Poly(N,N′-Diethylacrylamide)-Based Thermoresponsive Hydrogels with Double Network Structure
title_full Poly(N,N′-Diethylacrylamide)-Based Thermoresponsive Hydrogels with Double Network Structure
title_fullStr Poly(N,N′-Diethylacrylamide)-Based Thermoresponsive Hydrogels with Double Network Structure
title_full_unstemmed Poly(N,N′-Diethylacrylamide)-Based Thermoresponsive Hydrogels with Double Network Structure
title_short Poly(N,N′-Diethylacrylamide)-Based Thermoresponsive Hydrogels with Double Network Structure
title_sort poly(n,n′-diethylacrylamide)-based thermoresponsive hydrogels with double network structure
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692105/
https://www.ncbi.nlm.nih.gov/pubmed/33121186
http://dx.doi.org/10.3390/polym12112502
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