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Dysbindin deficiency Alters Cardiac BLOC-1 Complex and Myozap Levels in Mice

Dysbindin, a schizophrenia susceptibility marker and an essential constituent of BLOC-1 (biogenesis of lysosome-related organelles complex-1), has recently been associated with cardiomyocyte hypertrophy through the activation of Myozap-RhoA-mediated SRF signaling. We employed sandy mice (Dtnbp1_KO),...

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Detalles Bibliográficos
Autores principales: Borlepawar, Ankush, Schmiedel, Nesrin, Eden, Matthias, Christen, Lynn, Rosskopf, Alexandra, Frank, Derk, Lüllmann-Rauch, Renate, Frey, Norbert, Rangrez, Ashraf Yusuf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692170/
https://www.ncbi.nlm.nih.gov/pubmed/33142804
http://dx.doi.org/10.3390/cells9112390