Cargando…

Dysbindin deficiency Alters Cardiac BLOC-1 Complex and Myozap Levels in Mice

Dysbindin, a schizophrenia susceptibility marker and an essential constituent of BLOC-1 (biogenesis of lysosome-related organelles complex-1), has recently been associated with cardiomyocyte hypertrophy through the activation of Myozap-RhoA-mediated SRF signaling. We employed sandy mice (Dtnbp1_KO),...

Descripción completa

Detalles Bibliográficos
Autores principales:	Borlepawar, Ankush, Schmiedel, Nesrin, Eden, Matthias, Christen, Lynn, Rosskopf, Alexandra, Frank, Derk, Lüllmann-Rauch, Renate, Frey, Norbert, Rangrez, Ashraf Yusuf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692170/ https://www.ncbi.nlm.nih.gov/pubmed/33142804 http://dx.doi.org/10.3390/cells9112390

Ejemplares similares

SH3-Binding Glutamic Acid Rich-Deficiency Augments Apoptosis in Neonatal Rat Cardiomyocytes
por: Deshpande, Anushka, et al.
Publicado: (2021)

The E3 ubiquitin ligase HectD3 attenuates cardiac hypertrophy and inflammation in mice
por: Rangrez, Ashraf Yusuf, et al.
Publicado: (2020)

Dysbindin is a potent inducer of RhoA–SRF-mediated cardiomyocyte hypertrophy
por: Rangrez, Ashraf Yusuf, et al.
Publicado: (2013)

Fibin regulates cardiomyocyte hypertrophy and causes protein-aggregate-associated cardiomyopathy in vivo
por: Petersen, Matthias, et al.
Publicado: (2023)

FYCO1 Regulates Cardiomyocyte Autophagy and Prevents Heart Failure Due to Pressure Overload In Vivo
por: Kuhn, Christian, et al.
Publicado: (2021)

Cardiac transcriptional and metabolic changes following thoracotomy
por: Heckmann, Markus B., et al.
Publicado: (2020)

The plaque protein myozap identified as a novel major component of adhering junctions in endothelia of the blood and the lymph vascular systems
por: Pieperhoff, Sebastian, et al.
Publicado: (2012)

Heart Failure Severity Closely Correlates with Intestinal Dysbiosis and Subsequent Metabolomic Alterations
por: Spehlmann, Martina E., et al.
Publicado: (2022)

The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins, and role in neurite outgrowth
por: Ghiani, CA, et al.
Publicado: (2009)

MicroRNA miR-301a is a novel cardiac regulator of Cofilin-2
por: Rangrez, Ashraf Yusuf, et al.
Publicado: (2017)

Data on the role of cardiac α-actin (ACTC1) gene mutations on SRF-signaling
por: Rangrez, Ashraf Yusuf, et al.
Publicado: (2020)

SUMO proteins in the cardiovascular system: friend or foe?
por: Shetty, Prithviraj Manohar Vijaya, et al.
Publicado: (2020)

RhoA Signaling in Immune Cell Response and Cardiac Disease
por: Kilian, Lucia Sophie, et al.
Publicado: (2021)

Dysbindin-1 Involvement in the Etiology of Schizophrenia
por: Wang, Haitao, et al.
Publicado: (2017)

Adapted clustering method for generic analysis of histological fibrosis staining as an open source tool
por: Remes, Anca, et al.
Publicado: (2023)

Dataset of ileum bacterial diversity in mice after heart failure due to pressure overload
por: Spehlmann, Martina E., et al.
Publicado: (2022)

SRF: a seriously responsible factor in cardiac development and disease
por: Deshpande, Anushka, et al.
Publicado: (2022)

Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus
por: Larimore, Jennifer, et al.
Publicado: (2017)

RhoA: a dubious molecule in cardiac pathophysiology
por: Kilian, Lucia Sophie, et al.
Publicado: (2021)

Dysbindin-1, BDNF, and GABAergic Transmission in Schizophrenia
por: Jun, Rachel, et al.
Publicado: (2022)

Exploring the Involvement of Gut Microbiota in Cancer Therapy-Induced Cardiotoxicity
por: Kunika,, et al.
Publicado: (2023)

MeCP2 Regulates the Synaptic Expression of a Dysbindin-BLOC-1 Network Component in Mouse Brain and Human Induced Pluripotent Stem Cell-Derived Neurons
por: Larimore, Jennifer, et al.
Publicado: (2013)

TRIM32 is an E3 ubiquitin ligase for dysbindin
por: Locke, Matthew, et al.
Publicado: (2009)

Dysbindin-1 genotype effects on emotional working memory
por: Wolf, Claudia, et al.
Publicado: (2009)

Behavioral characterization of mice overexpressing human dysbindin-1
por: Shintani, Norihito, et al.
Publicado: (2014)

Dysbindin-1 regulates mitochondrial fission and gamma oscillations
por: Zhao, Jun, et al.
Publicado: (2021)

Sumoylation-independent activation of Calcineurin-NFAT-signaling via SUMO2 mediates cardiomyocyte hypertrophy
por: Bernt, Alexander, et al.
Publicado: (2016)

Effect of the Dysbindin Gene on Antimanic Agents in Patients with Bipolar I Disorder
por: Yun, Dong-Hwan, et al.
Publicado: (2008)

Dysbindin-Associated Proteome in the P2 Synaptosome Fraction of Mouse Brain
por: Han, Meng-Hsuan J., et al.
Publicado: (2014)

Variations in Dysbindin-1 are associated with cognitive response to antipsychotic drug treatment
por: Scheggia, Diego, et al.
Publicado: (2018)

Periprocedural Changes of NT‐proBNP Are Associated With Survival After Transcatheter Aortic Valve Implantation
por: Seoudy, Hatim, et al.
Publicado: (2019)

Elevated high-sensitivity troponin T levels at 1-year follow-up are associated with increased long-term mortality after TAVR
por: Seoudy, Hatim, et al.
Publicado: (2020)

To Bloc or Not to Bloc: Challenges in the Management of Patients Requesting “En-Bloc Capsulectomy”
por: Johal, Kavan S, et al.
Publicado: (2020)

Dysbindin Modulates Prefrontal Cortical Glutamatergic Circuits and Working Memory Function in Mice
por: Jentsch, J. David, et al.
Publicado: (2009)

Dysbindin Promotes the Post-Endocytic Sorting of G Protein-Coupled Receptors to Lysosomes
por: Marley, Aaron, et al.
Publicado: (2010)

Dysbindin facilitates invasion and metastasis by promoting phosphorylation of ERK in epithelial ovarian cancer
por: Lv, Xiaohui, et al.
Publicado: (2020)

Reduced Rate of Neural Differentiation in the Dentate Gyrus of Adult Dysbindin Null (Sandy) Mouse
por: Nihonmatsu-Kikuchi, Naomi, et al.
Publicado: (2011)

Increased dysbindin-1B isoform expression in schizophrenia and its propensity in aggresome formation
por: Xu, Yiliang, et al.
Publicado: (2015)

Publisher Correction: Variations in Dysbindin-1 are associated with cognitive response to antipsychotic drug treatment
por: Scheggia, Diego, et al.
Publicado: (2018)

Dysbindin links presynaptic proteasome function to homeostatic recruitment of low release probability vesicles
por: Wentzel, Corinna, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_svp3bh75d9hvcereip1lpojn7j