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Conditional Ablation of Myeloid TNF Improves Functional Outcome and Decreases Lesion Size after Spinal Cord Injury in Mice

Spinal cord injury (SCI) is a devastating condition consisting of an instant primary mechanical injury followed by a secondary injury that progresses for weeks to months. The cytokine tumor necrosis factor (TNF) plays an important role in the pathophysiology of SCI. We investigated the effect of mye...

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Detalles Bibliográficos
Autores principales: Ellman, Ditte Gry, Lund, Minna Christiansen, Nissen, Maiken, Nielsen, Pernille Sveistrup, Sørensen, Charlotte, Lester, Emilie Boye, Thougaard, Estrid, Jørgensen, Louise Helskov, Nedospasov, Sergei A., Andersen, Ditte Caroline, Stubbe, Jane, Brambilla, Roberta, Degn, Matilda, Lambertsen, Kate Lykke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692197/
https://www.ncbi.nlm.nih.gov/pubmed/33153044
http://dx.doi.org/10.3390/cells9112407

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