Frequent Germline and Somatic Single Nucleotide Variants in the Promoter Region of the Ribosomal RNA Gene in Japanese Lung Adenocarcinoma Patients

Ribosomal RNA (rRNA), the most abundant non-coding RNA species, is a major component of the ribosome. Impaired ribosome biogenesis causes the dysfunction of protein synthesis and diseases called “ribosomopathies,” including genetic disorders with cancer risk. However, the potential role of rRNA gene...

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Detalles Bibliográficos
Autores principales: Ohashi, Riuko, Umezu, Hajime, Sato, Ayako, Abé, Tatsuya, Kondo, Shuhei, Daigo, Kenji, Sato, Seijiro, Hara, Norikazu, Miyashita, Akinori, Ikeuchi, Takeshi, Motoyama, Teiichi, Kishi, Masashi, Nagaoka, Tadahiro, Horiuchi, Keiko, Shiga, Atsushi, Okuda, Shujiro, Sekiya, Tomoki, Ohtsubo, Aya, Ichikawa, Kosuke, Kagamu, Hiroshi, Kikuchi, Toshiaki, Watanabe, Satoshi, Tanuma, Jun-Ichi, Schraml, Peter, Hamakubo, Takao, Tsuchida, Masanori, Ajioka, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692307/
https://www.ncbi.nlm.nih.gov/pubmed/33153169
http://dx.doi.org/10.3390/cells9112409

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