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A Universal Pharmacokinetic Model for Dexmedetomidine in Children and Adults

A universal pharmacokinetic model was developed from pooled paediatric and adult data (40.6 postmenstrual weeks, 70.8 years, 3.1–152 kg). A three-compartment pharmacokinetic model with first-order elimination was superior to a two-compartment model to describe these pooled dexmedetomidine data. Popu...

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Detalles Bibliográficos
Autores principales:	Morse, James D., Cortinez, L. Ignacio, Anderson, Brian J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692360/ https://www.ncbi.nlm.nih.gov/pubmed/33126702 http://dx.doi.org/10.3390/jcm9113480

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