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Allele-Specific PCR for KRAS Mutation Detection Using Phosphoryl Guanidine Modified Primers

Establishing the Kirsten rat sarcoma (KRAS) mutational status is essential in terms of managing patients with various types of cancer. Allele-specific real-time polymerase chain reaction (AS-PCR) is a widely used method for somatic mutations detection. To improve the limited sensitivity and specific...

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Detalles Bibliográficos
Autores principales:	Chubarov, Alexey S., Oscorbin, Igor P., Filipenko, Maxim L., Lomzov, Alexander A., Pyshnyi, Dmitrii V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692470/ https://www.ncbi.nlm.nih.gov/pubmed/33114622 http://dx.doi.org/10.3390/diagnostics10110872

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