Cargando…

Rab11A Functions as a Negative Regulator of Osteoclastogenesis through Dictating Lysosome-Induced Proteolysis of c-fms and RANK Surface Receptors

Osteoclast differentiation and activity are controlled by two essential cytokines, macrophage colony-stimulating factor (M-CSF) and the receptor activator of nuclear factor-κB ligand (RANKL). Rab11A GTPase, belonging to Rab11 subfamily representing the largest branch of Ras superfamily of small GTPa...

Descripción completa

Detalles Bibliográficos
Autores principales: Okusha, Yuka, Tran, Manh Tien, Itagaki, Mami, Sogawa, Chiharu, Eguchi, Takanori, Okui, Tatsuo, Kadowaki, Tomoko, Sakai, Eiko, Tsukuba, Takayuki, Okamoto, Kuniaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692573/
https://www.ncbi.nlm.nih.gov/pubmed/33142674
http://dx.doi.org/10.3390/cells9112384

Ejemplares similares