The Alpha-Lipoic Acid Improves Survival and Prevents Irinotecan-Induced Inflammation and Intestinal Dysmotility in Mice

Irinotecan, an anticancer drug, induces diarrhea and intestinal inflammation, resulting in an increase in the cost of care and in treatment delays. In this study, we investigated whether alpha-lipoic acid (α-LA) could improve irinotecan-mediated intestinal inflammation, diarrhea and dysmotility. Int...

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Detalles Bibliográficos
Autores principales: Costa, Daniely V. S., Costa, Deiziane V. S., Sousa, Caren N. S., Silva, Angeline M. H. P., Medeiros, Ingridy S., Martins, Dainesy S., Martins, Conceição S., Pequeno, Ana L. V., Lima-Júnior, Roberto C. P., Soares, Pedro M. G., Vasconcelos, Silvânia M. M., Brito, Gerly A. C., Souza, Emmanuel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692584/
https://www.ncbi.nlm.nih.gov/pubmed/33152996
http://dx.doi.org/10.3390/ph13110361

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