A Gene Expression High-Throughput Screen (GE-HTS) for Coordinated Detection of Functionally Similar Effectors in Cancer

SIMPLE SUMMARY: Approximately 30% of human cancer patients carry active Ras mutations, which play a central role in cancer cell malignancy. Although Ras serves as an excellent drug target, significant challenges still exist to directly inhibit all forms of oncogenic Ras. Identifying functionally sim...

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Detalles Bibliográficos
Autores principales: Rao, Chaitra, Huisman, Dianna H., Vieira, Heidi M., Frodyma, Danielle E., Neilsen, Beth K., Chakraborty, Binita, Hight, Suzie K., White, Michael A., Fisher, Kurt W., Lewis, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692652/
https://www.ncbi.nlm.nih.gov/pubmed/33120942
http://dx.doi.org/10.3390/cancers12113143

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