IL-2 and Anti-TGF-β Promote NK Cell Reconstitution and Anti-tumor Effects after Syngeneic Hematopoietic Stem Cell Transplantation

SIMPLE SUMMARY: Hematopoietic stem cell transplantation (HSCT) causes early immune deficiency and susceptibility to both opportunistic infections and cancer relapse. In this study, using a mouse model where donor cells can be tracked over time, we have observed that the combination of IL-2 (a cytoki...

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Detalles Bibliográficos
Autores principales: Alvarez, Maite, Dunai, Cordelia, Khuat, Lam T., Aguilar, Ethan G., Barao, Isabel, Murphy, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692743/
https://www.ncbi.nlm.nih.gov/pubmed/33138229
http://dx.doi.org/10.3390/cancers12113189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692743/
https://www.ncbi.nlm.nih.gov/pubmed/33138229
http://dx.doi.org/10.3390/cancers12113189

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