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IL-2 and Anti-TGF-β Promote NK Cell Reconstitution and Anti-tumor Effects after Syngeneic Hematopoietic Stem Cell Transplantation
SIMPLE SUMMARY: Hematopoietic stem cell transplantation (HSCT) causes early immune deficiency and susceptibility to both opportunistic infections and cancer relapse. In this study, using a mouse model where donor cells can be tracked over time, we have observed that the combination of IL-2 (a cytoki...
Autores principales: | Alvarez, Maite, Dunai, Cordelia, Khuat, Lam T., Aguilar, Ethan G., Barao, Isabel, Murphy, William J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692743/ https://www.ncbi.nlm.nih.gov/pubmed/33138229 http://dx.doi.org/10.3390/cancers12113189 |
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