Aerosolizable Lipid Nanoparticles for Pulmonary Delivery of mRNA through Design of Experiments

Messenger RNA is a class of promising nucleic acid therapeutics to treat a variety of diseases, including genetic diseases. The development of a stable and efficacious mRNA pulmonary delivery system would enable high therapeutic concentrations locally in the lungs to improve efficacy and limit poten...

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Detalles Bibliográficos
Autores principales: Zhang, Hairui, Leal, Jasmim, Soto, Melissa R., Smyth, Hugh D. C., Ghosh, Debadyuti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692784/
https://www.ncbi.nlm.nih.gov/pubmed/33143328
http://dx.doi.org/10.3390/pharmaceutics12111042

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