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Non-Invasive Measurement of Drug and 2-HG Signals Using (19)F and (1)H MR Spectroscopy in Brain Tumors Treated with the Mutant IDH1 Inhibitor BAY1436032

SIMPLE SUMMARY: Targeted therapies are of growing interest to physicians in cancer treatment. These drugs target specific genes and proteins involved in the growth and survival of cancer cells. Brain tumor therapy is complicated by the fact that not all drugs can penetrate the blood brain barrier an...

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Detalles Bibliográficos
Autores principales:	Wenger, Katharina J., Richter, Christian, Burger, Michael C., Urban, Hans, Kaulfuss, Stefan, Harter, Patrick N., Sreeramulu, Sridhar, Schwalbe, Harald, Steinbach, Joachim P., Hattingen, Elke, Bähr, Oliver, Pilatus, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692790/ https://www.ncbi.nlm.nih.gov/pubmed/33138036 http://dx.doi.org/10.3390/cancers12113175

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