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Hybrid of Restricted and Penalized Maximum Likelihood Method for Efficient Genome-Wide Association Study

In genome-wide association studies, linear mixed models (LMMs) have been widely used to explore the molecular mechanism of complex traits. However, typical association approaches suffer from several important drawbacks: estimation of variance components in LMMs with large scale individuals is comput...

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Detalles Bibliográficos
Autores principales:	Ren, Wenlong, Liang, Zhikai, He, Shu, Xiao, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692801/ https://www.ncbi.nlm.nih.gov/pubmed/33138126 http://dx.doi.org/10.3390/genes11111286

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